Emma Ciafaloni, MD is the Associate Professor of Neurology and Pediatrics at the University of Rochester School of Medicine and Dentistry, Department of Neurology, Rochester, New York.Patrick F. Chinnery, FRCP, FMedSci is the Director at the Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.Robert C. Griggs, MD is the Professor of Neurology, Medicine, Pediatrics, Pathology and Laboratory Medicine, at the Center for Human Experimental Therapeutics, University of Rochester School of Medicine and Dentistry, Department of Neurology, Rochester, New York.