Essential Guide to N-of-1 Trials in Health

Häftad, Engelska, 2016

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Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more.

Produktinformation

Utgivningsdatum2016-08-23
Mått155 x 235 x 20 mm
Vikt442 g
FormatHäftad
SpråkEngelska
Antal sidor245
FörlagSpringer
ISBN9789402404401

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Preface.- Introduction.- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences.- N-of-1 trials in medical contexts.- Aggregated N-of-1 trials.- Methodological considerations for N-of-1 trials.- Randomization, allocation concealment and blinding.- Data collection and quality control.- Individual reporting of N-of-1 trials to patients and clinicians.- Assessing and reporting adverse events.- Research ethics and N-of-1 trials.- Statistical analysis of N-of-1 trials.- The economics of N-of-1 trials.- Reporting N-of-1 trials to professional audiences.- Single patient open trials.- Systematic review and meta-analysis using N-of-1 trials.- Where are N-of-1 trials headed?- Index.

“This is a philosophical rethinking of thelimitations of randomized controlled trials and the value of cross-overexperiments conducted with a single patient. … This is a book for experiencedclinicians who are knowledgeable about current evidence-based treatmentmodalities and who can objectively recognize when to consider different optionsfor treatment.” (Vincent F. Carr, Doody’s Book Reviews, January 2016)