Erik K. St Louis, Department of Neurology, Mayo Clinic, Rochester, MN, USA.David M. Ficker, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA.Terence J. O’Brien, Departments of Medicine and Neurology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Vic, Australia.

• List of contributors ixForeword xiiiSection I: Quality of life and the interictal state in epilepsy1 Quality of life in epilepsy: the key importance of the interictal state 3David M. Ficker2 Comorbidities in epilepsy: range and impact 7J. Layne Moore and John O. Elliott3 Epilepsy, comorbidities, and consequences: implications for understanding and combating stigma 15Rosemarie Kobau, Colleen K. DiIorio, Nancy J. Thompson, Yvan A. Bamps, and Erik K. St. LouisSection II: Cognition and epilepsy4 Causes and types of cognitive domain impairments in epilepsy 29 Impairment of consciousness in epilepsy 31Luigi Maccotta, Clemente Vega, and R. Edward HoganIctal cognitive impairments due to nonconvulsive status epilepticus 38Elizabeth WaterhouseMemory and dysexecutive impairments in epilepsy 45Erik K. St. Louis and Ashley M. EnkeAttention deficit/hyperactivity disorder, disordered attention, and epilepsy 63David W. Dunn and William G. KronenbergerBehavioral and developmental disorders in epilepsy 68Michael Smith and Esmeralda L. Park5 Cognitive effects of epilepsy therapies 74Beth A. Leeman and Kimford J. Meador6 Autism and epilepsy 88Vladimýr Komárek7 Cognitive rehabilitation strategies in epilepsy 94Cher Stephenson and Robert D. JonesSection III: Adverse effects of epilepsy therapies8 Adverse effects in epilepsy: recognition, measurement, and taxonomy 103Frank G. Gilliam, Laura S. Snavely, and Piero Perucca9 Clinically important antiepileptic drug interactions and their influence on adverse effects in epilepsy 110Frank M.C. Besag and Philip N. Patsalos10 Minimizing the adverse effects of epilepsy therapies: principles and practice 120Erik K. St. Louis11 Idiosyncratic adverse side effects of antiepileptic drugs: risk, prevention, and counselling 127Mary L. Zupanc and Lily H. Tran12 Antiepileptic drug therapy and fetal development 136Frank J.E. VajdaSection IV: Mood state, psychiatric comorbidity, and epilepsy13 Mood state, anxiety, and psychosis in epilepsy 147Michael Salzberg14 The contribution of sleep and anxiety disorders to quality of life in people with epilepsy 159Dee Snape, Ann Jacoby, and Gus Baker15 Epilepsy and personality 171Christopher Turnbull, Simon Jones, Sophia J. Adams, and Dennis Velakoulis16 Psychogenic attacks and epilepsy 183Bláthnaid McCoy and Selim R. BenbadisSection V: General health and epilepsy 17Obesity and epilepsy 195Sandra J. Petty and Alison M. Pack18 Epilepsy in the elderly: vascular disease, the aging brain, and selection of appropriate therapies 203Katherine H. Noe and Joseph I. Sirven19 Balance disorders and falls in epilepsy 216Sandra J. Petty, Keith D. Hill, and John D. Wark20 Bone health in epilepsy 224Sandra J. Petty, and John D. Wark21 Sleep and epilepsy 230Irakli Kaolani and Erik K. St. Louis22 Use of complementary and alternative medicine in epilepsy 241Dana Ekstein and Steven C. Schachter23 Epilepsy and alcohol and substance abuse 252Ekrem Kutluay and Jonathan C. Edwards24 Driving, employment, and related issues in epilepsy 258Kristine Ziemba and Joe DrazkowskiIndex 267

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