Del 25 - Translational Epigenetics

Epigenetics of Exercise and Sports

Concepts, Methods, and Current Research

Häftad, Engelska, 2021

AvStuart M Raleigh,UK) Raleigh, Stuart M (Associate Professor in Exercise Biochemistry and Epigenetics, Research Centre for Sport, Exercise and Life Sciences, Faculty of Health and Life Science, Coventry University, Priory Street, Coventry,Stuart M. Raleigh

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Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research.

Thoroughly examines fundamental concepts in exercise and sports epigenetics, methods for new research, and known impacts for human physiology, disease, and clinical outcomes
Discusses exercise and sports epigenetics in relation to metabolism, obesity, aging, immunity, and neurological disease, concussion, and sports doping, among other topics
Includes preliminary information on exercise epigenetics and covid-19 infection
Features chapter contributions from international experts in the field

Produktinformation

Utgivningsdatum2021-07-15
Mått191 x 235 x 23 mm
Vikt660 g
FormatHäftad
SpråkEngelska
SerieTranslational Epigenetics
Antal sidor320
FörlagElsevier Science
ISBN9780128206829

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik

Stuart M Raleigh, BSc, FIBMS, PhD is an Associate Professor in Exercise Biochemistry and Epigenetics at Coventry University. His research interests focus on epigenetics, genetics, and biochemical mechanisms of chronic disease. He has a special interest in identifying epigenetic factors that influence the risk of musculoskeletal soft tissue pathologies and he is also exploring the link between miRNA expression and various exercise related traits. Dr. Raleigh led the University of Northampton’s Centre for Physical Activity and Chronic Disease (PACD) from 2014-2018 and he has extensive international research collaborations. His teaching interests focus on Alzheimer’s disease and multifactorial genetics. He is a Fellow of the Higher Education Academy (HEA), and Section Editor (Genetics theme) for the Journal of Sports Science and Medicine.

Section I Concepts and methods1. Exercise and sport: Definitions, classifications, and relevance to population health2. Epigenetic processes—An overview3. Methods to study exercise and sports epigeneticsSection II Current research and future perspectives4. Nutrients, metabolism, and epigenetic change5. Obesity epigenetics and exercise6. Epigenetic change and different types of exercise7. Exercise, epigenetics, and aging8. Epigenetics, exercise, and the immune system9. Alzheimer’s disease, epigenetics, and exercise10. The current and future state of sports genomics11. Epigenetic regulation and musculoskeletal injuries12. Sports concussion and epigenetics13. Epigenetics and doping in sports—The role of microRNAs14. Future perspectives and concluding remarks

"...covers what epigenetics is, how it works, and how aging, exercise, sport and even concussion change this…. [Will] help readers understand the relationship between exercise/sport and epigenetics in hopes to help the population be more active by enabling more customization to exercise and sports for the individual…. The best aspects of the book are the separate sections/chapters going over the research and role of each different variable with epigenetics. The author makes it easy for the novice to understand the concepts. The book does a fantastic job introducing epigenetics, the current research, and the future potential uses, [which] is incredibly useful to those in sports, lifestyle, and longevity medicine…. [V]ery well written and laid out thoughtfully for easy reference…. This book can be very useful for guidance, further workups and more for people interested in longevity, and optimization of their health using more than just the normal "diet and exercise." --©Doody’s Review Service, 2023, Jacob Pfeiffer, DO,MBA (Medical College of Wisconsin)

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