Dr. Tollefsbol is a Distinguished Professor at the University of Alabama at Birmingham. He holds doctorates in molecular biology and osteopathic medicine, trained with National Academy of Science members and has over 200 peer-reviewed publications. Reports highlighting the translatability to the lay public of the discoveries made in his laboratory have appeared in international media representing >50 million readers. Dr. Tollefsbol has been featured as an Investigator in the Spotlight by the NIH as well as a Scientist in the Spotlight by ScienceNow. He is an Associate Editor for Frontiers in Genetics, a contributor to Lewin’s GENES classic textbook and Lead Editor for Elsevier’s Translational Epigenetics Series. Dr. Tollefsbol has been named a “Highly Ranked Scholar” worldwide (ScholarGPS). He has been invited for numerous endowed keynote presentations, his research has been highlighted in eScience News and ScienceDaily and he has published 20 scholarly books on topics related to his research.

• Section I: Introduction1. Epigenetics of Human Disease: An OverviewSection II: Methodology2. Methods and Strategies to Determine Epigenetic Variation in Human Disease3. DNA Methylation–Based Measures of Biological Aging4. Bioinformatics of Epigenomic Data Generated From Next-Generation SequencingSection III: Human Cancer 5. DNA Methylation Alterations in Human Cancer6. Alterations of Histone Modifications in Cancer7. MicroRNA in Cancer8. Epigenetic Approaches to Cancer TherapySection IV: Neurological Disease9. Epigenetics in Neurobehavioral Disease10. Emerging Role of Epigenetics in Human Neurodevelopmental Disorders11. The Epigenetics of Alzheimer's and Other Neurodegenerative Disorders12. Epigenetic Modulation of Human Neurobiological DisordersSection V: Autoimmune Disease13. Epigenetic Basis of Autoimmune Disorders in Humans14. Approaches to Autoimmune Diseases Using Epigenetic TherapySection VI: Metabolic Disorders15. Epigenomics and Human Obesity16. Epigenetic Approaches to Control Obesity17. Early-Life Nutrition, Epigenetics and Prevention of Obesity18. Epigenetics of Diabetes in Humans19. The Potential of Epigenetic Compounds in Treating DiabetesSection VII: Other Disorders/Diseases20. Epigenetic-Processes Driven Disorders and Therapeutics21. Epigenetics of Allergic Diseases Allergies, Eczema, Asthma, and Rhinitis22. Therapy of Airway Disease:  Epigenetic Potential23. The Role of Epigenetics in Cardiovascular Disease 24. Epigenetic Treatment Approaches to Cardiovascular Disease25. Epigenetics and Human Infectious Diseases26. Therapy of Infectious Diseases Using Epigenetic Approaches27. Translational Aspects of the Endometriosis Epigenome28. Aberrant DNA Methylation Patterns in Gynecologic Cancers: Implications for Prevention and Therapy 29. Epigenetics in Human Reproduction and Gynecologic DiseasesSection VIII: Development, Aging and Transgenerational Effects30. Epigenetics of Transgenerational Inheritance of Disease31. Epigenomic Mechanisms of Human Developmental Disorders32. Therapeutic Approaches to Imprinting Diseases33. Stem Cell Epigenetics and Human Disease34. Noncoding RNA Regulatory Networks, Epigenetics, and Programming Stem Cell Renewal and Differentiation: Implications for Stem Cell Therapy35. Aging and Disease: The Epigenetic Bridge36. Epigenetic Programming of Human Disease and AgingSection IX: Future Research37. Epigenetic Prospects in Epidemiology and Public Health

Dr. Tollefsbol is a Distinguished Professor at the University of Alabama at Birmingham. He holds doctorates in molecular biology and osteopathic medicine, trained with National Academy of Science members and has over 200 peer-reviewed publications. Reports highlighting the translatability to the lay public of the discoveries made in his laboratory have appeared in international media representing >50 million readers. Dr. Tollefsbol has been featured as an Investigator in the Spotlight by the NIH as well as a Scientist in the Spotlight by ScienceNow. He is an Associate Editor for Frontiers in Genetics, a contributor to Lewin’s GENES classic textbook and Lead Editor for Elsevier’s Translational Epigenetics Series. Dr. Tollefsbol has been named a “Highly Ranked Scholar” worldwide (ScholarGPS). He has been invited for numerous endowed keynote presentations, his research has been highlighted in eScience News and ScienceDaily and he has published 20 scholarly books on topics related to his research.

• Section I: Introduction1. Epigenetics of Human Disease: An OverviewSection II: Methodology2. Methods and Strategies to Determine Epigenetic Variation in Human Disease3. DNA Methylation–Based Measures of Biological Aging4. Bioinformatics of Epigenomic Data Generated From Next-Generation SequencingSection III: Human Cancer 5. DNA Methylation Alterations in Human Cancer6. Alterations of Histone Modifications in Cancer7. MicroRNA in Cancer8. Epigenetic Approaches to Cancer TherapySection IV: Neurological Disease9. Epigenetics in Neurobehavioral Disease10. Emerging Role of Epigenetics in Human Neurodevelopmental Disorders11. The Epigenetics of Alzheimer's and Other Neurodegenerative Disorders12. Epigenetic Modulation of Human Neurobiological DisordersSection V: Autoimmune Disease13. Epigenetic Basis of Autoimmune Disorders in Humans14. Approaches to Autoimmune Diseases Using Epigenetic TherapySection VI: Metabolic Disorders15. Epigenomics and Human Obesity16. Epigenetic Approaches to Control Obesity17. Early-Life Nutrition, Epigenetics and Prevention of Obesity18. Epigenetics of Diabetes in Humans19. The Potential of Epigenetic Compounds in Treating DiabetesSection VII: Other Disorders/Diseases20. Epigenetic-Processes Driven Disorders and Therapeutics21. Epigenetics of Allergic Diseases Allergies, Eczema, Asthma, and Rhinitis22. Therapy of Airway Disease:  Epigenetic Potential23. The Role of Epigenetics in Cardiovascular Disease 24. Epigenetic Treatment Approaches to Cardiovascular Disease25. Epigenetics and Human Infectious Diseases26. Therapy of Infectious Diseases Using Epigenetic Approaches27. Translational Aspects of the Endometriosis Epigenome28. Aberrant DNA Methylation Patterns in Gynecologic Cancers: Implications for Prevention and Therapy 29. Epigenetics in Human Reproduction and Gynecologic DiseasesSection VIII: Development, Aging and Transgenerational Effects30. Epigenetics of Transgenerational Inheritance of Disease31. Epigenomic Mechanisms of Human Developmental Disorders32. Therapeutic Approaches to Imprinting Diseases33. Stem Cell Epigenetics and Human Disease34. Noncoding RNA Regulatory Networks, Epigenetics, and Programming Stem Cell Renewal and Differentiation: Implications for Stem Cell Therapy35. Aging and Disease: The Epigenetic Bridge36. Epigenetic Programming of Human Disease and AgingSection IX: Future Research37. Epigenetic Prospects in Epidemiology and Public Health

Dr. Tollefsbol is a Distinguished Professor at the University of Alabama at Birmingham. He holds doctorates in molecular biology and osteopathic medicine, trained with National Academy of Science members and has over 200 peer-reviewed publications. Reports highlighting the translatability to the lay public of the discoveries made in his laboratory have appeared in international media representing >50 million readers. Dr. Tollefsbol has been featured as an Investigator in the Spotlight by the NIH as well as a Scientist in the Spotlight by ScienceNow. He is an Associate Editor for Frontiers in Genetics, a contributor to Lewin’s GENES classic textbook and Lead Editor for Elsevier’s Translational Epigenetics Series. Dr. Tollefsbol has been named a “Highly Ranked Scholar” worldwide (ScholarGPS). He has been invited for numerous endowed keynote presentations, his research has been highlighted in eScience News and ScienceDaily and he has published 20 scholarly books on topics related to his research.

• Section I: Introduction1. Epigenetics of Human Disease: An OverviewSection II: Methodology2. Methods and Strategies to Determine Epigenetic Variation in Human Disease3. DNA Methylation–Based Measures of Biological Aging4. Bioinformatics of Epigenomic Data Generated From Next-Generation SequencingSection III: Human Cancer 5. DNA Methylation Alterations in Human Cancer6. Alterations of Histone Modifications in Cancer7. MicroRNA in Cancer8. Epigenetic Approaches to Cancer TherapySection IV: Neurological Disease9. Epigenetics in Neurobehavioral Disease10. Emerging Role of Epigenetics in Human Neurodevelopmental Disorders11. The Epigenetics of Alzheimer's and Other Neurodegenerative Disorders12. Epigenetic Modulation of Human Neurobiological DisordersSection V: Autoimmune Disease13. Epigenetic Basis of Autoimmune Disorders in Humans14. Approaches to Autoimmune Diseases Using Epigenetic TherapySection VI: Metabolic Disorders15. Epigenomics and Human Obesity16. Epigenetic Approaches to Control Obesity17. Early-Life Nutrition, Epigenetics and Prevention of Obesity18. Epigenetics of Diabetes in Humans19. The Potential of Epigenetic Compounds in Treating DiabetesSection VII: Other Disorders/Diseases20. Epigenetic-Processes Driven Disorders and Therapeutics21. Epigenetics of Allergic Diseases Allergies, Eczema, Asthma, and Rhinitis22. Therapy of Airway Disease:  Epigenetic Potential23. The Role of Epigenetics in Cardiovascular Disease 24. Epigenetic Treatment Approaches to Cardiovascular Disease25. Epigenetics and Human Infectious Diseases26. Therapy of Infectious Diseases Using Epigenetic Approaches27. Translational Aspects of the Endometriosis Epigenome28. Aberrant DNA Methylation Patterns in Gynecologic Cancers: Implications for Prevention and Therapy 29. Epigenetics in Human Reproduction and Gynecologic DiseasesSection VIII: Development, Aging and Transgenerational Effects30. Epigenetics of Transgenerational Inheritance of Disease31. Epigenomic Mechanisms of Human Developmental Disorders32. Therapeutic Approaches to Imprinting Diseases33. Stem Cell Epigenetics and Human Disease34. Noncoding RNA Regulatory Networks, Epigenetics, and Programming Stem Cell Renewal and Differentiation: Implications for Stem Cell Therapy35. Aging and Disease: The Epigenetic Bridge36. Epigenetic Programming of Human Disease and AgingSection IX: Future Research37. Epigenetic Prospects in Epidemiology and Public Health