Epigenetics and miRNA in Neurodegenerative Diseases

Nyhet

From Molecular Mechanisms to Clinical Applications

Häftad, Engelska, 2026

AvLance R. McMahon,Dharmendra Kumar Khatri,Balachandar Vellingiri

2 519 kr

Kommande

Epigenetics and miRNA in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications explores the crucial role of epigenetic modifications and microRNAs in the onset, progression, and treatment of neurodegenerative disorders such as Alzheimer’s, Parkinson’s, ALS, and Huntington’s disease. This comprehensive book bridges cutting-edge molecular research with real-world clinical applications, covering biomarker discovery, novel therapeutics, gene editing, and AI-driven bioinformatics. With clear explanations, case studies, and future perspectives, it serves as an essential resource for researchers, clinicians, and biotech professionals working toward innovative solutions for neurodegenerative disease diagnosis and treatment

Integrates perspectives from neuroscience, molecular biology, clinical medicine, and bioinformatics
Covers fundamental molecular mechanisms, disease specific applications, and translational research, appealing to both researchers and clinicians
Provides practical examples of epigenetic and miRNA research as applied to neurodegenerative diseases, aiding in real-world implementation

Produktinformation

Utgivningsdatum2026-12-01
Mått216 x 276 x undefined mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor325
FörlagElsevier Science
ISBN9780443448454

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik

Lance R. McMahon, Ph.D., serves as the Executive Vice President for Research and Innovation at Texas Tech University Health Sciences Center. In his position, Dr. McMahon will serve as chair of the Research Council. Additionally, he has a faculty appointment in the Jerry H. Hodge School of Pharmacy. Dr. Dharmendra Kumar Khatri is an Associate Professor in the Department of Pharmacology, NIMS Institute of Pharmacy at NIMS University Rajasthan, Jaipur, India. Dr. Balachandar Vellingiri currently is investigating various neurological diseases and developing human induced pluripotent stem cells (HiPSCs). Exploring the cutting-edge molecular, cellular, and translational neuroscience approaches, he aims to unravel disease mechanisms, identify therapeutic targets, and develop innovative interventions to slow or reverse neurological diseases. His expertise is on several techniques such as molecular cytogenetics, pathway analysis, and techniques in developing HiPSCs and Brain organoids, especially for neurological diseases.

Section I: Fundamentals of Epigenetics and miRNA in Neurodegeneration1. Introduction to Epigenetics and miRNA in neurodegenerative diseases2. Epigenetic Mechanisms in the Nervous System3. miRNA Biogenesis and Function in Brain HealthSection II: Epigenetics and miRNA in Specific Neurodegenerative Disorders4. Alzheimer’s Disease: Epigenetic and miRNA Contributions5. Parkinson’s Disease: The Role of Epigenetic Modifications6. Huntington’s Disease: Epigenetic and Post-Transcriptional Control7. Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD): Molecular Crosstalk8. Multiple Sclerosis: Epigenetic and miRNA Influence on NeuroinflammationSection III: Translational and Clinical Applications9. Epigenetic Biomarkers in Neurodegenerative Diseases10. miRNA-Based Therapeutics: Challenges and Opportunities11. Pharmacological and Nutritional Epigenetics in Neuroprotection12. Gene Editing and Epigenetic Engineering Approaches13. Artificial Intelligence and Computational Epigenomics in NeurodegenerationSection IV: Future Perspectives and Ethical Considerations14. Personalized Medicine in Neurodegenerative Diseases: The Role of Epigenetics and miRNA15. Ethical, Legal, and Social Implications of Epigenetic and miRNA-Based Therapies