Del 38 - Progress in Molecular and Subcellular Biology

Epigenetics and Chromatin

Häftad, Engelska, 2008

2 069 kr

Beställningsvara. Skickas inom 10-15 vardagar

Fri frakt för medlemmar vid köp för minst 249 kr.

Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence. This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.

Produktinformation

Utgivningsdatum2008-09-10
Mått155 x 235 x 16 mm
Vikt435 g
FormatHäftad
SpråkEngelska
SerieProgress in Molecular and Subcellular Biology
Antal sidor266
Upplaga2005
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783540852360

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik

Chromatin Remodeling Factors and DNA Replication.- Epigenetic Inheritance of Chromatin States Mediated by Polycomb and Trithorax Group Proteins in Drosophila.- How to Pack the Genome for a Safe Trip.- Chromatin Modifications on the Inactive X Chromosome.- Chromatin Mechanisms in Drosophila Dosage Compensation.- DNA Methylation in Epigenetic Control of Gene Expression.- The Epigenetic Breakdown of Cancer Cells: From DNA Methylation to Histone Modifications.- Developmental Regulation of the ?-Globin Gene Locus.- Epigenetic Regulation of Mammalian Imprinted Genes: From Primary to Functional Imprints.- Seed Development and Genomic Imprinting in Plants.

From the reviews:"This book contains ten excellent chapters … . Thoroughly covers a rapidly developing and expanding field. The different chapters are well written and provide clear, concise and informative views on the topic. Notably, each chapter ends with a conclusion describing current models and future challenges in epigenetics. … both the expert and the novice will find this book a valuable source of information on the various epigenetic phenomena." (Frank Sauer, Nature Cell Biology, Vol. 7 (10), October, 2005)"Professor Philippe Jeanteur, who is one of the editors of this PMSB Springer series, coordinated a well reknown group of scientists working on epigenetics to provide us with an updated collection of papers treating epigenetic phenomena in Mammals, insects and plants. Well done: careful presentations, well illustrated and rich in bibliography, this book is a must for those interested in epigenetics." (Carlo Alberto Redi, European Journal of Histochemistry, Vol. 49 (4), 2005)