Business and technology specialists from North America, the UK, and Singapore provide 10 essays on the relationship between innovation, entrepreneurship, and technology platforms. They discuss entrepreneurship and entrant-incumbent dynamics and their competition, including negotiating for the market, types of innovation projects funded by financiers, and product innovation using disruptive technology prior to and after sales takeoff in the robotics industry; innovation and technology adoption within large incumbent firms, including the relationship between organizational complexity and innovation, the effects of the destabilizing of a social network on network externalities, and managerial and organizational challenges firms and senior teams face in transitioning from traditionally closed ways of conducting business to externally focused platform, ecosystem, and innovation strategies; and platform-based competition, with discussion of strategies of the platform provider, the impact of a platform on firms that interact with it, and extension of the platform literature to biotechnology.