Del 384 i serien Current Topics in Microbiology and Immunology

Endogenous ADP-Ribosylation

Inbunden, Engelska, 2014

1 439 kr

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This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections:· Evolution and detection of endogenous ADP-ribosylation· ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs)· ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs)The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives.

Produktinformation

Utgivningsdatum2014-11-13
Mått155 x 235 x 18 mm
Vikt506 g
FormatInbunden
SpråkEngelska
SerieCurrent Topics in Microbiology and Immunology
Antal sidor213
Upplaga2015
FörlagSpringer International Publishing AG
ISBN9783319107707

Tillhör följande kategorier

The natural history of ADP-ribosyltransferases and the ADP ribosylation system.- Identification and Analysis of ADP-ribosylated Proteins.- Photorhabdus luminescens toxins TccC3 and TccC5: Insecticidal ADP-ribosyltransferases that modify threonine and glutamine.- Reaction mechanism of mono-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein.- Regulation of nitrogenase by reversible mono-ADP-ribosylation.- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.- Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish.- Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family.- Function and regulation of the mono-ADP-ribosyltransferase ARTD10.- Regulation of nucleocytoplasmic transport by ADP-ribosylation: the emerging role of karyopherin-β1 mono-ADP-ribosylation by ARTD15.