Emerging Viral Diseases

In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event. Table of Contents Front Matter Workshop Overview A1 Animal Reservoirs of Middle East Respiratory Syndrome Coronavirus--Jonathan H. Epstein and Kevin J. Olival A2 Chikungunya at the Door - Dj Vu All Over Again?--David M. Morens and Anthony S. Fauci A3 Emerging Infectious Diseases: Threats to Human Health and Global Stability--David M. Morens and Anthony S. Fauci A4 Emerging Infectious Diseases in 2012: 20 Years After the Institute of Medicine Report--David M. Morens and Anthony S. Fauci A5 Pandemic Preparedness and Response - Lessons from the H1N1 Influenza of 2009--Harvey V. Fineberg A6 Studying Zoonotic Diseases in the Natural Host--John W. Lowenthal, Michelle L. Baker, Cameron R. Stewart, Christopher Cowled, Celine Deffrasnes, Lin-Fa Wang, and Andrew G. D. Bean A7 Medusa's Ugly Head Again: From SARS to MERS-CoV--Trish M. Perl, Allison McGeer, and Connie Savor Price A8 The Relationship Between Eco-social System Changes, the AnimalHuman Interface, and Viral Disease Emergence--Dirk U. Pfeiffer A9 From Risk Analysis to Risk Governance - Adapting to an Ever More Complex Future--Dirk U. Pfeiffer A10 A One Health Perspective on HPAI H5N1 in the Greater Mekong Sub-region--Dirk U. Pfeiffer, Martin J. Otte, David Roland-Holst, and David Zilberman A11 Zoonosis Emergence Linked to Agricultural Intensification and Environmental Change--Bryony A. Jones, Delia Grace, Richard Kock, Silvia Alonso, Jonathan Rushton, Mohammed Y. Said, Declan McKeever, Florence Mutua, Jarrah Young, John McDermott, and Dirk U. Pfeiffer A12 Global Trends in Emerging Viral Diseases of Wildlife Origin--Jonathan Sleeman and Hon Ip A13 Role of Poultry in Spread of Novel H7N9 Influenza Virus in China--Mary J. Pantin-Jackwood, Patti J. Miller, Erica Spackman, David E. Swayne, Leonardo Susta, Mar Costa-Hurtado, and David L. Suarez Appendix B: Agenda Appendix C: Acronyms Appendix D: Glossary Appendix E: Speaker Biographies