Emerging Technologies for Heart Diseases

Volume 2: Treatments for Myocardial Ischemia and Arrhythmias

Inbunden, Engelska, 2020

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The increasing pace of advances in cardiology throughout the last few decades has fundamentally altered the natural course of heart patients. In the last few years, available therapies have been revolutionized completely by new transcatheter therapeutic approaches, novel ventricular assist devices, and new drugs. Also, molecular biology and genetics have a rapidly growing impact on cardiovascular diseases, enabling the field of regenerative medicine to become increasingly closer to routine clinical implementation.

Emerging Technologies for Heart Diseases was conceived to cover the recent extensive literature on current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, and the second covers myocardial ischemia and arrhythmias. The clinical topic is addressed in several chapters divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each of the 46 chapters focuses on clinically available solutions, new therapies currently under evaluation in clinical trials, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested in a preclinical model. Also, the book discusses future challenges and opportunities for clinical implementation. Lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas.

Overall, this textbook was designed for physicians who want to stay up-to-date with current therapies and those of the future, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options.

Provides a comprehensive review of the latest therapeutic developments for heart failure, valvular disorders, myocardial ischemia and arrhythmias, and their clinical implications
Written by both specialists in the field and established researchers, it delivers a review of emerging medical technologies and presents insight into their therapeutic promise
Chapters are arranged according to disease pathogeneses and relevance and include coverage of the mechanical, electrophysiological, and biological approaches for the management of patients with myocardial ischemia and arrhythmias

Produktinformation

Utgivningsdatum2020-08-19
Mått216 x 276 x 34 mm
Vikt1 790 g
FormatInbunden
SpråkEngelska
Antal sidor730
FörlagElsevier Science
ISBN9780128137048

Tillhör följande kategorier

Biologi inom Naturvetenskap och teknik
Hjärt- och kärlsjukdomar inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Udi Nussinovitch, MD, PhD graduated from the Sackler Faculty of Medicine, Tel Aviv University, training at the Sheba Medical Center, Rambam Healthcare Center and Meir Medical Center, while concurrently graduating with a PhD in cardiac electrophysiology from the Technion Institute of Technology, Israel.Dr Nussinovitch has dedicated his research to investigating novel therapeutic approaches for cardiac disorders and the modulation of the cardiac electrophysiologic substrate for therapeutic purposes. He serves as director of the Applicative Cardiovascular Research Center (ACRC), affiliated to Tel Aviv University. Dr Nussinovitch founded several biotech companies, and has been the recipient of several research awards. He carries out his clinical work at the Meir Medical Center, a medical facility and leading referral center in Israel.

SECTION 5: Treatment of ischemic heart disease24. Coronary Balloon Angioplasty, Stenting, and Bioabsorbable Scaffolds25. Coronary thrombectomy 26. Coronary atherectomy and treatments for calcified coronary lesions27. Treatment of chronic total occlusion 28. Minimally-invasive device-based approaches for improving cardiac perfusion29. Gene therapy approaches to cardiac neovascularization and protection from ischemia SECTION 6: Treatment and prevention of ventricular tachyarrhythmias30. The past, present and future of implantable electrical defibrillators 31. Electrophysiological mapping and cardiac ablation therapy for the prevention of ventricular arrhythmias32. Gene and cell therapy approaches for the prevention and treatment of ventricular arrhythmia SECTION 7: Treatment and prevention of supraventricular tachyarrhythmias33. Ablation therapy and implantable device-based approaches for supraventricular arrhythmias34. Gene and cell-based therapies for the prevention and treatment of supraventricular arrhythmias SECTION 8: Treatment and prevention of bradyarrhythmias35. Cardiac rhythm devices of today and tomorrow 36. Molecular therapies for bradyarrhythmias37. Cell therapy approaches for treatment of bradyarrhythmias 38. Optogenetics for cardiac pacing and termination of arrhythmias39. Non-optognetic approaches for leadless cardiac pacing SECTION 9: Flexible electronics for cardiac monitoring and therapy40. Organ Conformal Electronics for Cardiac TherapeuticsSECTION 10: Device-based therapies for prevention of cerebral embolization41. Embolic protection devices for stroke prevention during cardiac interventions42. Percutaneous closure of the left atrial appendage　for stroke prevention43. Devices for continuous embolic protection SECTION 11: Noninvasive methods for structural heart defects44. Transcatheter closure of atrial septal defect in adults45. Catheter-based treatments for ventricular septal defects SECTION 12: Novel treatments for hypertension46. Non-pharmacological therapies for uncontrolled hypertension

"This second volume provides excellent, in-depth information on state-of-the-art techniques and emerging innovations in various cardiovascular procedures such as coronary angioplasty, stenting and bioabsorbable scaffolds, atherectomy, mechanical thrombectomy, treatment of chronic total occlusions, left atrial appendage closure, and embolic protection devices. The quality and content of this book is exceptional. The book is ideal for physicians and researchers in the advanced stages of cardiovascular training." --Doody Reviews