Drug Delivery

• Part I. Introductory material1: Introduction2: Drug administration and drug effectivenessPart II. Fundamentals3: Diffusion and drug dispersion4: Diffusion in biological systems5: Drug permeation through biological barriers6: Drug transport by fluid motion7: Pharmacokinetics of drug distributionPart III. Drug delivery systems8: Drug modification9: Controlled drug delivery systems10: Case studies in drug delivery11: PostscriptAppendix A. Overview of polymeric biomaterialsA1. Nondegradable polymersA2. Biodegradable polymersA3. Water-soluble polymersAppendix B. Useful data and nomenclatureB1. Physiological parametersB2. Cardiovascular systemB3. Clinical chemistryB4. Permeation and diffusionB5. Protein propertiesB6. Mathematical tables and functionsB7. NomenclatureIndex

"Providing a working foundation in the principles underlying drug transport, reaction, and disappearance in physiological and pathological situations, this introduction and guide covers a range of topics, including drug and protein properties, drug modification and diffusion, and polymeric biomaterials. Case studies, physiological guidelines, and useful nomenclature and data are also featured. Saltzman teaches chemical engineering at CornellUniversity."--SciTech Book News"[A]n excellent addition to the library of any scientist interested in drug delivery systems. Unlike others in the area, this volume is focused on quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological conditions. ... even a scientist who may lack a background in mathematics could benefit from this unique discussion of engineering concepts. ... what makes this book outstanding is theability of the author to discus mathematical equations grounded in real examples. ... The book is highly recommended as a textbook in the field of drug delivery ..."--The Quarterly Review of Biology"Providing a working foundation in the principles underlying drug transport, reaction, and disappearance in physiological and pathological situations, this introduction and guide covers a range of topics, including drug and protein properties, drug modification and diffusion, and polymeric biomaterials. Case studies, physiological guidelines, and useful nomenclature and data are also featured. Saltzman teaches chemical engineering at CornellUniversity."--SciTech Book News"[A]n excellent addition to the library of any scientist interested in drug delivery systems. Unlike others in the area, this volume is focused on quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological conditions. ... even a scientist who may lack a background in mathematics could benefit from this unique discussion of engineering concepts. ... what makes this book outstanding is theability of the author to discus mathematical equations grounded in real examples. ... The book is highly recommended as a textbook in the field of drug delivery ..."--The Quarterly Review of Biology