Del i serien Nanotechnology in Biomedicine

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers

Häftad, Engelska, 2025

AvRajendra Awasthi,Santosh Kumar Singh,Anurag Kumar Singh

3 519 kr

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Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers delivers an up-to-date and complete overview of the range of biomedical applications for porous silicon nanomaterials, with a special emphasis on drug delivery. This book introduces the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, such as vaccine development, drug delivery, and tissue engineering. It also contains new insights on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, cancer immunotherapy, and more. Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers is of interest to researchers in the fields of materials science, nanotechnology, pharmaceutical science, biomedical engineering, and cancer research.

Details synthesis approaches and methodologies for porous silicon-based nanocarriers, enabling structural understanding and therapeutic applications
Highlights the role of silica nanoparticles in targeted drug delivery, emphasizing their impact on cancer therapy, immunotherapy, neurodegenerative disorders, and other biomedical applications
Explores clinical aspects and trials of silica nanoparticles for treatment options

Produktinformation

Utgivningsdatum2025-10-22
Mått152 x 229 x 30 mm
Vikt960 g
FormatHäftad
SpråkEngelska
SerieNanotechnology in Biomedicine
Antal sidor600
FörlagElsevier Science
ISBN9780443248023

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Rajendra Awasthi is Professor of Pharmaceutics at Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India. Santosh Kumar Singh is a Senior Scientist at the Centre of Experimental Medicine & Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. Dr. Anurag Kumar Singh is a Research Associate (ICMR-RA) in the Department of Pharmaceutical Engineering and Technology at IIT BHU, Varanasi. He earned his PhD from the Centre of Experimental Medicine and Surgery, IMS, BHU, and an M. Pharm from Central University of Rajasthan. With more than 3.5 years of postdoctoral experience, he has worked at Alabama State University (Cancer Biology Research and Training) and Bar-Ilan University (Institute of Nanotechnology & Advanced Materials, Israel). His research centers on nano-particulate systems for chronic pain, neurodegenerative disorders, and brain-targeted drug delivery, including dendrimers, nanoporous silica/silicon materials, and polymeric nanoparticles for controlled delivery. He aims to develop nanomedicines for biomedical applications and to bridge engineering, pharmaceutical, and medical research. He has published widely, including reviews/editorials, and authored/editor of four books and over ten book chapters.

1. Historical advancements in targeted nanoscale drug delivery systems2. Synthesis of Porous Silicon-based Nanoparticles3. Characterization techniques for mesoporous silicon nanoparticles4. Mesoporous silicon for solubility enhancement of drugs5. Porous silicon-based nanocarriers for tumor targeting6. Porous silicon and related composites for topical drug delivery7. Porous silicon nanocarriers for the management of neurodegenerative disorders8. Functionalized silica nanocarriers for brain targeted delivery9. Porous silicon-based materials in nanoneedle and microneedle-based drug delivery systems10. Porous silicon-based drug delivery carriers in cancer management11. Stimuli-responsive silica nanoparticles: Smart systems for controlled drug delivery12. Mesoporous silica-based nanocarriers in pulmonary drug delivery13. Porous silicon nanoparticles for improved cellular uptake and targeted drug delivery14. Recent advances in porous silicon-based technology for biomedical applications15. Immunotherapeutic applications of porous silicon nanoparticles16. Bioengineered porous silicon nanoparticles in vaccine development17. Bioavailability enhancement of poorly soluble drugs with mesoporous silicon18. Silica nanoparticles in clinical trials19. Mesoporous silica nanoparticles for therapeutic uses: from bench to clinics20. Future perspectives of mesoporous silica-based nanocarriers in drug delivery