Drug Adherence in Hypertension and Cardiovascular Protection

Michel Burnier is Professor of Medicine and head of the Nephrology and Hypertension Consultation division at the University Hospital of Lausanne, Switzerland. He trained in internal medicine and nephrology in Lausanne, Switzerland and at the University of Colorado Health Science Centre in Denver, Colorado. He is a member of the Scientific Council of the European Society of Hypertension and member of the Committee of the Swiss Society of Hypertension. He was president of the Swiss Society of Nephrology and of the Swiss Society of Hypertension. Burnier is a member of the editorial board of several international journals in the field of hypertension and nephrology.His research interests are the renal mechanisms of hypertension and the pathogenesis of disease progression in chronic kidney diseases with an emphasis on the role of sodium. He has also worked on the clinical pharmacology of new antihypertensive drugs in humans with a focus on drugs affecting the renin-angiotensin system and on drug adherence. In 2010, he received the JM Métry Compliance Award of the ESPACOMP, the European Society of Drug Adherence.

• 1 Taxonomy of adherence.- I Measuring drug adherence.- 2 Qualitative assessment of adherence.- 3 Electronic monitoring of drug adherence.- 4 Measurements of drugs in plasma/urine.- 5 Assessing adherence measurement in large databases.- 6 Direct observed treatment in hypertension.- 7 Novel technologies for following drug adherence.- 8 Ethical aspects of measuring adherence II Risk factors for non-adherence.- 9 Determinants and barriers to adherence in CV diseases.- 10 Beliefs and adherence.- III Adherence in hypertension and CV protection.-  11 Impact of drug adherence in clinical trials.- 12 Drug adherence in essential hypertension: impact of drugs.- 13 Persistence in hypertension in general practice.- 14 Drug adherence in resistant hypertension.- 15 Drug adherence with cardiovascular medicines (statins).- 16 Adherence and cardiovascular risk.- IV Interventions to improve drug adherence.-  17 Which interventions are useful?.- 18 Use of fixed-dose combinations in CV diseaseprevention.- 19 Nurse-led intervention in Hypertension.- 20 Role of the Pharmacist in supporting adherence.-  21 Integrated approaches to support adherence.-  22 Use of Apps to improve drug adherence.-  V Health care consequences of non-adherence.- 23 Global clinical consequence of poor adherence.- 24 Cost of non-adherence.