Dose Optimization in Drug Development

Inbunden, Engelska, 2006

Av Rajesh Krishna, USA) Krishna, Rajesh (Merck and Company, Inc., Rahway, New Jersey

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This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug applications. Compiling key issues and current research on safety, efficacy, and clinical pharmacology, and PK-PD, this volume critically highlights the multidisciplinary nature of drug development and spans the fields of pharmacokinetics, clinical pharmacology, biostatistics, and experimental medicine.

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