Dopamine and Sleep

Jaime M. Monti is Professor, Department of Pharmacology and Therapeutics, School of Medicine, Clinics Hospital, University of the Republic, Uruguay. He is a member of the International College of Neuropsychopharmacology, Sleep Research Society (USA), European Sleep Research Society, and the Argentinian Society of Sleep Medicine.S.R. Pandi-Perumal, M.Sc., has authored many publications in the field of sleep and biological rhythms. He has published a number of books on various aspects of sleep medicine with Springer: Neuroendocrine Correlates of Sleep/wakefulness (Springer USA, 2005); Sleep and Sleep Disorders: a Neuropsychopharmacological approach (Landes Bioscience/Eurekha.com and Springer SBM, USA, 2006); Clinical Pharmacology of Sleep (Birkhauser-Verlag, Switzerland, 2006); Neuroimmunology of Sleep (Springer-Verlag, USA, 2007); Primary Care Sleep Medicine (Humana Press/Springer-Verlag, USA, 2007); Serotonin: physiology, functions, and regulation (Birkhauser-Verlag, Switzerland, 2008); Sleep and Quality of life in medical illness, (Humana/Springer, USA, 2008); Narcolepsy: a clinical guide (Springer, 2010); GABA and Sleep: Molecular, Functional, and Clinical Aspects (Birkhauser-Verlag, Switzerland, 2010).S. Chokroverty MD, FRCP is a co-director of Neurology at the New Jersey Neuroscience Institute, JKF Medical Center, Edison, New Jersey, USA. He is a also a Professor of Neuroscience at Seton Hall University School of Graduate Medical Education, South Orange, New Jersey.

• 1. Dopamine – Historical aspects.- 2. Dopamine receptors – The dopamine transporter.- 3.  The effect of dopamine receptor agonists on the sleep-wake cycle.- 4. Dopamine and its receptors: circadian aspects.- 5. Excitation of ventral tegmental area dopaminergic neurons by orexins/hypocretins.- 6. Role of the basal ganglia in the control of sleep and wakefulness.- 7. Mesolimbic dopamine and impulse control disorders.- 8. Sleep and Parkinson´s disease.- 9. Regulation and modulation of depression-related behaviors: role of dopaminergic 15 Neurons.- 10. Dopamine dysfunction in schizophrenia and its treatment.- 11. Schizophrenia: dopamine/glutamate interactions.- 12. Sleep in schizophrenia and the effect of antipsychotic drugs.

“The purpose is to increase awareness of the latest developments in this multidisciplinary field. … It is meant for those interested in or specializing in the treatment of patients with sleep disorders across a variety of disciplines. This book is an interdisciplinary, cutting-edge guide for sleep disorder specialists, researchers, psychiatrists, neurologists, pulmonologists, and behavioral sleep medicine specialists. It also may be of interest to those involved in drug development in this area.” (Michael Easton, Doody's Book Reviews, March, 2016)