This book provides an overview of direct methods, such as limit and shakedown analysis, which are intended for avoiding cumbersome step-by-step calculations to determine the limit states of mechanical structures under monotone, cyclic or variable actions with unknown loading history. The book comprises several contributions that demonstrate how tremendous advances in numerical methods, especially in optimization, have contributed to the success of direct methods and their applicability to practical engineering problems in structural mechanics and mechanics of materials. The contents reflect the outcomes of the workshop “Direct Methods for Limit State of Materials and Structures,” held in Cosenza, Italy in June 2022.