Dietary Sugar, Salt and Fat in Human Health

Harry G. Preuss, MD, MACN, CNS, received his BA and MD from Cornell University, trained for three years in internal medicine at Vanderbilt University Medical Center under Dr. David E. Rogers, studied as a fellow in renal physiology at Cornell University Medical Center under Dr. Robert F. Pitts, and spent two years in clinical and research training in nephrology at Georgetown University Medical Center under Dr. George E. Schreiner. During his training years, he was a special research fellow of the National Institutes of Health (NIH). Following give years as an assistant and associate (tenured) professor of medicine at the University of Pittsburgh Medical Center where he became an established investigator of the American Heart Association, he returned to Georgetown Medical Center. He subsequently performed a 6-month sabbatical in molecular biology at the NIH in the laboratories of Dr. Maurice Burg. Dr. Preuss is now a tenured Professor in 4 departments at Georgetown University Medical Center – Biochemistry, Physiology, Medicine, and Pathology. His bibliography includes over 250 peer-reviewed, original medical research papers, 215 general medical contributions (chapters, review articles, etc.), 7 patents, and more than 260 abstracts. Dr. Preuss has written, edited or co-edited 12 books and 3 symposia published in well-established journals. Debasis Bagchi, PhD, MACN, CNS, MAIChE, received his Ph.D. in Medicinal Chemistry in 1982. He is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy, Houston, TX, and Chief Scientific Officer at Cepham Research Center, Piscataway, NJ, Adjunct Faculty in Texas Southern University, Houston, TX. He served as the Senior Vice President of Research & Development of InterHealth Nutraceuticals Inc, Benicia, CA, from 1998 until Feb 2011, and then as Director of Innovation and Clinical Affairs, of Iovate Health Sciences, Oakville, ON, until June 2013. Dr. Bagchi received the Master of American College of Nutrition Award in October 2010. He is the Past Chairman of International Society of Nutraceuticals and Functional Foods (ISNFF), Past President of American College of Nutrition, Clearwater, FL, and Past Chair of the Nutraceuticals and Functional Foods Division of Institute of Food Technologists (IFT), Chicago, IL. He is serving as a Distinguished Advisor on the Japanese Institute for Health Food Standards (JIHFS), Tokyo, Japan. Dr. Bagchi is a Member of the Study Section and Peer Review Committee of the National Institutes of Health (NIH), Bethesda, MD. He has published 321 papers in peer reviewed journals, 30 books, and 18 patents. Dr. Bagchi is also a Member of the Society of Toxicology, Member of the New York Academy of Sciences, Fellow of the Nutrition Research Academy, and Member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, OH. He is also Associate Editor for the Journal of Functional Foods, Journal of the American College of Nutrition, and the Archives of Medical and Biomedical Research, and is also serving as Editorial Board Member of numerous peer reviewed journals, including Antioxidants & Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, and The Original Internist, among others.

• General Background1. Epidemiological Perspectives of Dietary Sugars, Salts and Fats2. Advancing Age, Influence of Dietary Sugars, Salts and Fats on Metabolic Disorders and Chronic Diseases3. Dietary Fat, Salt and Sugar: A clinical perspective of the social catastrophe4. Influences of Food Ingredients on Enterohepatic Circulation of Bile Acids5. Anemia: Influence of Dietary Fat, Sugar and Salt on Hemoglobin and Blood HealthFood Behavior, Food Addiction and Metabolic Syndrome6. Drivers of Food Behavior 7. Focusing the Fight Against Processed Food Addiction (PFA)8. Dietary Influences on Pediatric Obesity and Metabolic Syndrome9. An Overview of Addiction to SugarDietary Sugar And Health10. Influence of Dietary Sugars on Blood Pressure Regulation: Historical, Epidemiological, Laboratory, and Clinical Considerations11. Glycation induced protein aggregation and cellular toxicity: An insight into the disease realm of high dietary sugar intake12. Probing Various Pro and Con Health Aspects of the Glucose-Insulin System in Non-Diabetics: Focusing on Insulin Resistance and Dietary Implications13. Evaluating Proposed Surrogates to Estimate Insulin Resistance in Non-Diabetics: Emphasizing Ratio Triglycerides/HDL-Cholesterol vs. Fasting Blood Glucose14. Associations of high blood sugar with oxidative stress and inflammation in patients with type 2 diabetes15. Assessing The Triglyceride/Hdl-Cholesterol Ratio As A Surrogate For Insulin Resistance And Its Link To The Metabolic Syndrome In Hispanics And African-Americans16. The benefit of Indian Jaggery over sugar on human health17. Linking Fasting Blood Glucose (FBG) Quartiles of Non-Diabetic Volunteers Ages 21-84 Years to Metabolic Syndrome ComponentsOverindulgence Of Dietary Salt18. Salt-Induced Inappropriate Augmentation of Intrarenal RAAS System: Chronic Renal Diseases19. Table Salt (Sodium Chloride): Vital Aspects Of Metabolism And Blood Pressure Regulation In Health And Disease20. Nutraceuticals and functional foods in the prevention of Hypertension induced by excessive intake of dietary saltDietary Fat & Cholesterol21. Physiological Role of Cholesterol in Human Body22. Interplay between dietary sugars and fats and insulin resistance23. Erythrocyte membranes in metabolic and neurological diseases – supplementation with fatty acids and membranes remodelingDietary Fiber, Ketogenic Diets & Benefits24. Dietary Fiber: A Functional Food Ingredient with Physiological Benefits25. Ketogenic and low carbohydrate diets in health and disease26. Dietary Fat, Salt and Sugar - A Teenager’s ViewCommentary from the Editors' Desk