Diagnostic Pathology: Placenta

Amy Heerema-McKenney, MD is Director of Perinatal Pathology at the Robert J. Tomsich Pathology and Laboratory Medicine Institute, Division of Anatomic Pathology for Cleveland Clinic in Cleveland, Ohio Edwina J. Popek, DO, is Professor Emeritus of Pathology, Immunology and Pediatrics, Baylor College of Medicine, Texas Children's Hospital Pavilion for Women in Houston, Texas Monique De Paepe, MD, MSc is Professor of Pathology and Laboratory Medicine at Women and Infants Hospital, Alpert Medical School of Brown University in Providence, Rhode Island

• SECTION 1: OVERVIEW OF GROSS AND MICROSCOPIC CHANGES UMBILICAL CORD EXTRAPLACENTAL MEMBRANES CHORIONIC PLATE STEM VILLI CHORIONIC VILLI SECTION 2: PLACENTAL DIAGNOSES SEPTA, INTERVILLOUS SPACE, AND BASAL PLATE DECIDUA MECONIUM INTRAUTERINE INFLAMMATION/INFECTION PLACENTAL INFECTIONS WITH VILLITIS AND OTHER FINDINGS CHRONIC INFLAMMATORY LESIONS MASSIVE PERIVILLOUS FIBRIN DEPOSITION AND MATERNAL FLOOR INFARCTION FETAL VASCULAR MALPERFUSION MATERNAL VASCULAR MALPERFUSION VILLOUS HYPERVASCULAR LESIONS GESTATIONAL TROPHOBLASTIC DISEASE, RELATED LESIONS, AND OTHER TUMORS PLACENTAL MESENCHYMAL DYSPLASIA SECTION 3: PLACENTAL EVALUATION IN SPECIAL CIRCUMSTANCES DIABETES IN PREGNANCY AND MATERNAL OBESITY PREECLAMPSIA AND MATERNAL VASCULAR MALPERFUSION FETAL-MATERNAL HEMORRHAGE FETAL HYDROPS INTRAUTERINE GROWTH RESTRICTION PREMATURITY ABNORMAL PLACENTAL IMPLANTATION INTRAUTERINE FETAL DEMISE MULTIPLE GESTATIONS MATERNAL COMPLICATIONS OF PREGNANCY SECTION 4: APPENDIX REFERENCE CHARTS FOR PLACENTAL EVALUATION SAMPLE TEMPLATES FOR PLACENTAL EVALUATION

"...an extensive overview of placental pathology, addressing both gross and microscopic changes, common diagnoses, and special circumstances in placental evaluation.... Unique structural elements of the book include consistently templated chapters, bulleted content for key areas, annotated images, and reference tables that facilitate quick and efficient access to relevant information.... The book provides an easy guide for trainees to use as they learn how to approach placenta histology and common entities.... It serves as an invaluable tool for practicing pathologists who need detailed and up-to-date information on placental pathology. Additionally, students and residents will find it beneficial for its clear and concise explanations, extensive visual aids, and structured presentation, which supports effective learning and retention of complex concepts.... an exceptionally high-quality resource [which] combines thorough coverage of placental pathology with clear and accessible writing, making it a valuable tool for both seasoned practitioners and those new to the field." ©Doody's Book Review Service, 2025, Meredith K Herman, DO (University of Michigan Medical School)