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Manzoor Ahmad Mir - Developing Costimulatory Molecules for Immunotherapy of Diseases, Häftad

Häftad, Engelska, 2015

Developing Costimulatory Molecules for Immunotherapy of Diseases

Av Manzoor Ahmad Mir

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Beskrivning

Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation.

The text aims to provide the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families, with the hope that targeting these families will yield new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases.



  • Highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy
  • Provides the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families
  • Targets new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases
Produktinformation
  • Utgivningsdatum: 2015-05-27
  • Mått: 152 x 229 x 20 mm
  • Vikt: 540 g
  • Format: Häftad
  • Språk: Engelska
  • Antal sidor: 322
  • Förlag: Elsevier Science
  • ISBN: 9780128025857
Utforska kategorier
Mer information

Dr. Manzoor Ahmad Mir holds a Master's in Zoology from HNBG Central University and completed his Ph.D. in Immunology at Jawaharlal Nehru University, New Delhi, and CSIR-Institute of Microbial Technology, Chandigarh. His research focuses on cancer biology, combination therapy in breast cancer, and tuberculosis immunology. Dr. Mir has published over 50 high-impact research papers and book chapters. He has authored more than 15 books with international publishers of repute. He serves on the editorial boards of prestigious journals. He is a member of several scientific organizations, including the American Association of Cancer Research and the Royal British Society. He has received the TARE Fellowship and the SRFP-2019 from the Indian Science Academies. Dr. Mir teaches Cancer Biology and Immunology at the University of Kashmir, where he heads the Department of Bioresources.

Recensioner i media

"...a solid framework to understand costimulation and its role in selected diseases...best serves as a fundamental review of costimulation with clinical correlates for the basic-science researcher." --Annals of Allergy, Asthma & Immunology

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