Wayne Katon, MD, is Professor of Psychiatry, Director of the Division of Health Services and Epidemiology, and Vice Chair of the Department of Psychiatry and Behavioral Sciences at the University of Washington Medical School. He is Director of a NIMH-funded National Research Service Award Primary Care-Psychiatry Fellowship that has successfully trained psychiatrists and primary care physicians for academic leadership positions. Dr. Katon is internationally renowned for his research on the prevalence of anxiety and depressive disorders in primary care, the relationship of psychiatric disorders to medically unexplained symptoms such as headache and fatigue, and the impact of depression and anxiety on patients with chronic medical illness. In recent years, his research has focused on developing innovative models of integrating mental health professionals and other allied health personnel into primary care to improve the care of patients with major depression and panic disorder.Dr. Katon has been awarded the American for Excellence in Teaching in Primary Care numerous times. He also has been awarded the Academy of Psychosomatic Medicine Research Award (1993) and the American Psychiatric Association Senior Scholar Health Services Research Award (1999) and the Depression and Bipolar Support Alliance Gerald L. Klerman Senior Investigator Award (2003). He is Editor-in-Chief of General Hospital Psychiatry and is honored by being one of the Web of Science Highly Cited Authors.Dr. Katon has written over 400 peer-reviewed journal articles and chapters, as well as Panic Disorder in the Medical Setting, a book for primary care physicians. In addition, Dr. Katon and his research team have written a self-help book for depressed patients titled Depression: Self-Care Companion for Better Living. Mario Maj is Professor of Psychiatry and Chairman at the University of Naples, Italy. He is President of the World Psychiatric Association and former President of the European Psychiatric Association. He is the Italian psychiatrist with the highest number of citations in indexed journals in the period 1981-2008.Norman Sartorius served as Director of the Division of Mental Health of the World Health Organization (WHO) and was the principal investigator of several major international studies on schizophrenia, on depression and on health service delivery. He has published more than 330 articles in scientific journals, authored or co-authored several books and edited a number of others.He was the President of the World Psychiatric Association (WPA) and President of the Association of European Psychiatrists (AEP). Currently he is the President of the Association for the Improvement of Mental Health Programmes and holds professorial appointments at the Universities of London, Prague and Zagreb and at several other universities in the USA and China.Professor Sartorius is a corresponding member of the Croatian Academy of Arts and Sciences and of the Spanish Royal Academy of Medicine, member of the Medical Academies of Croatia, Peru and Mexico. He has honorary doctorates from the Universities of Umea, Prague and Bath and is an Honorary Fellow or honorary member of numerous psychiatric associations. He is also the editor of three journals and a member of the editorial board of many more.

• List of Contributors viiPreface ix1 The Epidemiology of Depression and Diabetes 1Cathy E. Lloyd, Norbert Hermanns, Arie Nouwen, Frans Pouwer, Leigh Underwood and Kirsty Winkley2 Unraveling the Pathogenesis of the Depression–Diabetes Link 29Khalida Ismail3 Medical Costs of Depression and Diabetes 63Leonard E. Egede4 Treatment of Depression in Patients with Diabetes: Efficacy, Effectiveness and Maintenance Trials, and New Service Models 81Wayne Katon and Christina van der Felz-Cornelis5 Diabetes and Depression: Management in Ordinary Clinical Conditions 109Richard Hellman and Paul Ciechanowski6 Depression and Diabetes: Sociodemographic and Cultural Aspects and Public Health Implications 143Juliana Chan, Hairong Nan and Rose TingAcknowledgement 173Index 175

"Depression and Diabetes is an outstanding book that provides and impressive amount of information on a major worldwide health problem that requires concerted efforts by the global community of health providers, including health care policy makers. The book is highly recommended and is well worth the short time commitment needed to read it." (Journal of Clinical Psychiatry, 2011) "Particularly helpful to mental health clinicians is the attention to both diabetes and mental health issues ... It explores an area of medicine that is important to our patients, their families, and all of us as we strive to provide better evidence-based treatments throughout the world." (Journal of Nervous and Mental Disease, 11 November 2011)"Depression and Diabetes does a good job in laying out the various biopsychosocial pathways by which diabetes might lead to depression or vice versa . . . the chapters in this book that will be most appreciated by clinical health psychologists and other practitioners who care for patients with diabetes are those involving treatment, either just the treatment of comorbid depression or concurrent treatment of both condition." (PsycCRITIQUES, 1 June 2011)"The present miniseries, Depression and Diabetes, Depression and Heart Disease and Depression and Cancer is a unique initiative to make physical diseases visible in psychiatry and to support the treatment ... To this reviewer the books have two strengths: their thematic broadness and the practical approach. The chapters about how to act clinically are excellent, pragmatic and consequently written .... The idea behind the series is excellent and the books are marvellous. After having read them no one will doubt that psychiatry is a medical speciality (that psychiatrists must be physicians first, psychiatrists next, that psychiatry must be done by psychiatrists and psychiatry must be lead by psychiatrists.)" (Acta Psychiatrica Scandinavica, 2011)"Diabetes and Depression will appeal to anyone with an academic interest in the links between diabetes and depression". (Diabetes Digest, 1 November 2010)

Wayne Katon, MD, is Professor of Psychiatry, Director of the Division of Health Services and Epidemiology, and Vice Chair of the Department of Psychiatry and Behavioral Sciences at the University of Washington Medical School. He is Director of a NIMH-funded National Research Service Award Primary Care-Psychiatry Fellowship that has successfully trained psychiatrists and primary care physicians for academic leadership positions. Dr. Katon is internationally renowned for his research on the prevalence of anxiety and depressive disorders in primary care, the relationship of psychiatric disorders to medically unexplained symptoms such as headache and fatigue, and the impact of depression and anxiety on patients with chronic medical illness. In recent years, his research has focused on developing innovative models of integrating mental health professionals and other allied health personnel into primary care to improve the care of patients with major depression and panic disorder.Dr. Katon has been awarded the American for Excellence in Teaching in Primary Care numerous times. He also has been awarded the Academy of Psychosomatic Medicine Research Award (1993) and the American Psychiatric Association Senior Scholar Health Services Research Award (1999) and the Depression and Bipolar Support Alliance Gerald L. Klerman Senior Investigator Award (2003). He is Editor-in-Chief of General Hospital Psychiatry and is honored by being one of the Web of Science Highly Cited Authors.Dr. Katon has written over 400 peer-reviewed journal articles and chapters, as well as Panic Disorder in the Medical Setting, a book for primary care physicians. In addition, Dr. Katon and his research team have written a self-help book for depressed patients titled Depression: Self-Care Companion for Better Living. Mario Maj is Professor of Psychiatry and Chairman at the University of Naples, Italy. He is President of the World Psychiatric Association and former President of the European Psychiatric Association. He is the Italian psychiatrist with the highest number of citations in indexed journals in the period 1981-2008.Norman Sartorius served as Director of the Division of Mental Health of the World Health Organization (WHO) and was the principal investigator of several major international studies on schizophrenia, on depression and on health service delivery. He has published more than 330 articles in scientific journals, authored or co-authored several books and edited a number of others.He was the President of the World Psychiatric Association (WPA) and President of the Association of European Psychiatrists (AEP). Currently he is the President of the Association for the Improvement of Mental Health Programmes and holds professorial appointments at the Universities of London, Prague and Zagreb and at several other universities in the USA and China.Professor Sartorius is a corresponding member of the Croatian Academy of Arts and Sciences and of the Spanish Royal Academy of Medicine, member of the Medical Academies of Croatia, Peru and Mexico. He has honorary doctorates from the Universities of Umea, Prague and Bath and is an Honorary Fellow or honorary member of numerous psychiatric associations. He is also the editor of three journals and a member of the editorial board of many more.

• List of Contributors viiPreface ix1 The Epidemiology of Depression and Diabetes 1Cathy E. Lloyd, Norbert Hermanns, Arie Nouwen, Frans Pouwer, Leigh Underwood and Kirsty Winkley2 Unraveling the Pathogenesis of the Depression–Diabetes Link 29Khalida Ismail3 Medical Costs of Depression and Diabetes 63Leonard E. Egede4 Treatment of Depression in Patients with Diabetes: Efficacy, Effectiveness and Maintenance Trials, and New Service Models 81Wayne Katon and Christina van der Felz-Cornelis5 Diabetes and Depression: Management in Ordinary Clinical Conditions 109Richard Hellman and Paul Ciechanowski6 Depression and Diabetes: Sociodemographic and Cultural Aspects and Public Health Implications 143Juliana Chan, Hairong Nan and Rose TingAcknowledgement 173Index 175

"Depression and Diabetes is an outstanding book that provides and impressive amount of information on a major worldwide health problem that requires concerted efforts by the global community of health providers, including health care policy makers. The book is highly recommended and is well worth the short time commitment needed to read it." (Journal of Clinical Psychiatry, 2011) "Particularly helpful to mental health clinicians is the attention to both diabetes and mental health issues ... It explores an area of medicine that is important to our patients, their families, and all of us as we strive to provide better evidence-based treatments throughout the world." (Journal of Nervous and Mental Disease, 11 November 2011)"Depression and Diabetes does a good job in laying out the various biopsychosocial pathways by which diabetes might lead to depression or vice versa . . . the chapters in this book that will be most appreciated by clinical health psychologists and other practitioners who care for patients with diabetes are those involving treatment, either just the treatment of comorbid depression or concurrent treatment of both condition." (PsycCRITIQUES, 1 June 2011)"The present miniseries, Depression and Diabetes, Depression and Heart Disease and Depression and Cancer is a unique initiative to make physical diseases visible in psychiatry and to support the treatment ... To this reviewer the books have two strengths: their thematic broadness and the practical approach. The chapters about how to act clinically are excellent, pragmatic and consequently written .... The idea behind the series is excellent and the books are marvellous. After having read them no one will doubt that psychiatry is a medical speciality (that psychiatrists must be physicians first, psychiatrists next, that psychiatry must be done by psychiatrists and psychiatry must be lead by psychiatrists.)" (Acta Psychiatrica Scandinavica, 2011)"Diabetes and Depression will appeal to anyone with an academic interest in the links between diabetes and depression". (Diabetes Digest, 1 November 2010)

Wayne Katon, MD, is Professor of Psychiatry, Director of the Division of Health Services and Epidemiology, and Vice Chair of the Department of Psychiatry and Behavioral Sciences at the University of Washington Medical School. He is Director of a NIMH-funded National Research Service Award Primary Care-Psychiatry Fellowship that has successfully trained psychiatrists and primary care physicians for academic leadership positions. Dr. Katon is internationally renowned for his research on the prevalence of anxiety and depressive disorders in primary care, the relationship of psychiatric disorders to medically unexplained symptoms such as headache and fatigue, and the impact of depression and anxiety on patients with chronic medical illness. In recent years, his research has focused on developing innovative models of integrating mental health professionals and other allied health personnel into primary care to improve the care of patients with major depression and panic disorder.Dr. Katon has been awarded the American for Excellence in Teaching in Primary Care numerous times. He also has been awarded the Academy of Psychosomatic Medicine Research Award (1993) and the American Psychiatric Association Senior Scholar Health Services Research Award (1999) and the Depression and Bipolar Support Alliance Gerald L. Klerman Senior Investigator Award (2003). He is Editor-in-Chief of General Hospital Psychiatry and is honored by being one of the Web of Science Highly Cited Authors.Dr. Katon has written over 400 peer-reviewed journal articles and chapters, as well as Panic Disorder in the Medical Setting, a book for primary care physicians. In addition, Dr. Katon and his research team have written a self-help book for depressed patients titled Depression: Self-Care Companion for Better Living. Mario Maj is Professor of Psychiatry and Chairman at the University of Naples, Italy. He is President of the World Psychiatric Association and former President of the European Psychiatric Association. He is the Italian psychiatrist with the highest number of citations in indexed journals in the period 1981-2008.Norman Sartorius served as Director of the Division of Mental Health of the World Health Organization (WHO) and was the principal investigator of several major international studies on schizophrenia, on depression and on health service delivery. He has published more than 330 articles in scientific journals, authored or co-authored several books and edited a number of others.He was the President of the World Psychiatric Association (WPA) and President of the Association of European Psychiatrists (AEP). Currently he is the President of the Association for the Improvement of Mental Health Programmes and holds professorial appointments at the Universities of London, Prague and Zagreb and at several other universities in the USA and China.Professor Sartorius is a corresponding member of the Croatian Academy of Arts and Sciences and of the Spanish Royal Academy of Medicine, member of the Medical Academies of Croatia, Peru and Mexico. He has honorary doctorates from the Universities of Umea, Prague and Bath and is an Honorary Fellow or honorary member of numerous psychiatric associations. He is also the editor of three journals and a member of the editorial board of many more.

• List of Contributors viiPreface ix1 The Epidemiology of Depression and Diabetes 1Cathy E. Lloyd, Norbert Hermanns, Arie Nouwen, Frans Pouwer, Leigh Underwood and Kirsty Winkley2 Unraveling the Pathogenesis of the Depression–Diabetes Link 29Khalida Ismail3 Medical Costs of Depression and Diabetes 63Leonard E. Egede4 Treatment of Depression in Patients with Diabetes: Efficacy, Effectiveness and Maintenance Trials, and New Service Models 81Wayne Katon and Christina van der Felz-Cornelis5 Diabetes and Depression: Management in Ordinary Clinical Conditions 109Richard Hellman and Paul Ciechanowski6 Depression and Diabetes: Sociodemographic and Cultural Aspects and Public Health Implications 143Juliana Chan, Hairong Nan and Rose TingAcknowledgement 173Index 175

"Depression and Diabetes is an outstanding book that provides and impressive amount of information on a major worldwide health problem that requires concerted efforts by the global community of health providers, including health care policy makers. The book is highly recommended and is well worth the short time commitment needed to read it." (Journal of Clinical Psychiatry, 2011) "Particularly helpful to mental health clinicians is the attention to both diabetes and mental health issues ... It explores an area of medicine that is important to our patients, their families, and all of us as we strive to provide better evidence-based treatments throughout the world." (Journal of Nervous and Mental Disease, 11 November 2011)"Depression and Diabetes does a good job in laying out the various biopsychosocial pathways by which diabetes might lead to depression or vice versa . . . the chapters in this book that will be most appreciated by clinical health psychologists and other practitioners who care for patients with diabetes are those involving treatment, either just the treatment of comorbid depression or concurrent treatment of both condition." (PsycCRITIQUES, 1 June 2011)"The present miniseries, Depression and Diabetes, Depression and Heart Disease and Depression and Cancer is a unique initiative to make physical diseases visible in psychiatry and to support the treatment ... To this reviewer the books have two strengths: their thematic broadness and the practical approach. The chapters about how to act clinically are excellent, pragmatic and consequently written .... The idea behind the series is excellent and the books are marvellous. After having read them no one will doubt that psychiatry is a medical speciality (that psychiatrists must be physicians first, psychiatrists next, that psychiatry must be done by psychiatrists and psychiatry must be lead by psychiatrists.)" (Acta Psychiatrica Scandinavica, 2011)"Diabetes and Depression will appeal to anyone with an academic interest in the links between diabetes and depression". (Diabetes Digest, 1 November 2010)