Dentist's Drug and Prescription Guide

The authors Mea A. Weinberg, DMD, MSD, RPh, is a Clinical Professor in the Ashman Department of Periodontology and Implant Dentistry at New York University College of Dentistry in New York, NY, USA. Stuart J. Froum, DDS, is an Adjunct Clinical Professor and Director of Clinical Research in the Ashman Department of Periodontology and Implant Dentistry at New York University College of Dentistry in New York, NY, USA. Stuart L. Segelnick, DDS, MS, is an Adjunct Associate Professor of Oral Medicine at the University of Pennsylvania School of Dental Medicine and an Adjunct Clinical Professor in the Ashman Department of Periodontology and Implant Dentistry at New York University College of Dentistry in New York, NY, USA.

• List of Contributors viiPreface ix1 Introduction to Pharmacology 11.1 Definition of Terms 11.2 Pharmacokinetics 31.3 Pharmacodynamics 82 The Prescription and Drug Names 132.1 Parts of a Prescription 132.2 Generic Substitution 142.3 Controlled Drugs 162.4 Principles of Prescription Writing 182.5 How to Avoid Prescription Errors 243 Basic Prescribing and Drug Dosing for the Dental Patient 293.1 Basic Principles of Drug Dosing 293.2 Pediatric Patients 323.3 Pregnant and Nursing Patients 383.4 Elderly Patients 423.5 Patients with Renal Impairment 423.6 Patients with Hepatic Impairment 453.7 Patients with History of Bariatric Surgery 494 Dental Formularies: Drugs Prescribed in Dentistry 554.1 Antimicrobials, Systemic 554.2 Antimicrobials, Local 774.3 Controlled- Release Drug Delivery 794.4 Antivirals/ Antifungal Agents 794.5 Prescribing for Acute Dental Pain 874.6 Prevention and Management of Opioid Prescription Drug Misuse 1114.7 Oral Sedation 1124.8 Glucocorticosteroids 1165 How to Manage Potential Drug Interactions in Dentistry 1275.1 Introduction to Drug Interactions 1275.2 Antibiotic–Drug Interactions in Dentistry 1325.3 Analgesic– Drug Interactions in Dentistry 1395.4 Sympathomimetic Agents and Drug Interactions in Dentistry 1415.5 Antianxiety Drug Interactions in Dentistry 1456 Evidence-Based Theory for Drug Prescribing in Dentistry 1496.1 General Considerations 1496.2 Prescribing for Inflammatory Periodontal Diseases and Periodontal Surgical Procedures 1516.3 Prescribing for Dental Implant Surgery 1606.4 Prescribing for Oral Surgery 1646.5 Prescribing for Odontogenic Infections 1647 Management of Medications Taken by Medically Complex Dental Patients 1777.1 American Heart Association Guidelines for Antibiotic Prophylaxis 1777.2 Antibiotic Prophylaxis for Total Joint Replacement 1817.3 Cardiovascular Diseases (Marc A. Singer, MD) 1837.4 Pregnant and Nursing Patient 2047.5 Corticosteroids and Thyroid Medication 2057.6 Asthma Medications 2077.7 Diabetes Medication 2097.8 Psychiatric and Neurological Medications 2127.9 Organ Transplantation (Antirejection) Medications 2267.10 Recreational and Illicit Drugs 2297.11 Antiresorptive Agents 2327.12 HIV/AIDS Research and Medications (Cheryl Barber, MPH, MSOD) 2388 Herbal, Dietary, and Natural Remedies 2718.1 Herbal–Drug Interactions 2718.2 Implications in Dentistry 273Appendix 1: Smoking Cessation Therapy 275Appendix 2: Oral Manifestation of Drugs 281Appendix 3: American Heart Association Antibiotic Prophylaxis Guidelines 287Index 289

“This second edition provides the reader with a timely and important update to the original textbook and shows the scientific basis for the drugs used in dentistry. It contains an extremely useful reference and guide to drugs used and prescribed in dental practices....This book provides the most current information, and is a “must read” for all dentists, dental residents and dental students.” - The New York State Dental Journal, June/July 2020“I do recommend this book for any dentist, even if they are not writing prescriptions. This book will help in working with people taking medications, legal, illicit, and over-the-counter, that affect the oral systemic system dentists concentrate on.” - The Journal of Craniomandibular & Sleep Practice, 2020, VOL. 38, NO. 4, 279