Deciphering The Role of Succinate Dehydrogenase in Drug Discovery

Dr. Vaishali M. Patil completed her bachelor’s in pharmacy from North Maharashtra University (MS), masters in pharmaceutical chemistry from Dr. A. P. J. Abdul Kalam Technical University (UP) and doctorate from Birla Institute of Technology, Ranchi, India. Dr. Patil is Associate Professor and Principal at Charak School of Pharmacy, Chaudhary Charan Singh University, Meerut, India. She has served as Visiting Professor, Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia. Dr. Patil has more than 17 years of experience in academics and research. Her research interest is in rational drug design with specialization in quantitative structure-activity relationship studies of biologically active molecules, drug-receptor interactions, and synthesis of small heterocyclic molecules. Dr. Patil has published more than 90 research articles in the peer-reviewed journals and authored numerous books and book chapters.Dr. Dileep Kumar received his B. Pharm from Manipal College of Pharmaceutical Sciences, Manipal University, India, and M. Pharm from S.G.S.I.T.S Indore, Madhya Pradesh, India. He was awarded junior research fellowship by National Medicinal Plant Board (NMPB) New Delhi, senior research fellowship from University Grants Commission (UGC), teaching assistantship and institute post-doctoral fellowship from IIT (BHU) Varanasi, India. He worked as an assistant professor in Poona College of Pharmacy, Bharti Vidyapeeth University, Pune, India.  He published more than 100 papers in his academic career.Dr. Satya P. Gupta has served at Tata Institute of Fundamental Research (TIFR), Mumbai and as Professor at Birla Institute of Technology and Science, Pilani and then MIET as its Director-cum Professor of Eminence.  Prof. Gupta has worked as Professor in the department of applied sciences at National Institute of Technical Teachers’ Training and Research, Bhopal, India. Prof. Gupta has a very long standing of teaching quantum chemistry, pharmaceutical chemistry, biophysics, and drug design. He had obtained his M. Sc and D. Phil degrees from University of Allahabad, Allahabad, India in 1967 and 1971, respectively. For his work in drug design, he has bagged several honors and awards.

• Chapter 1. Succinate Dehydrogenase: Structure, Function and Significance.- Chapter 2. The Function of Succinate Dehydrogenase in Maintaining Normal Health.- Chapter 3. Role of Succinate Dehydrogenase in Cellular Respiration.- Chapter 4. Succinate Dehydrogenase: An Important Target in Drug Discovery for Tropical and Neglected Diseases.- Chapter 5. Succinate Dehydrogenase in Mitochondrial Disorders.- Chapter 6. Role of SDH in Cardiovascular Disorders.- Chapter 7. Implication of Succinate Dehydrogenase in Cancer.- Chapter 8. SDH and its Impact on Neurodegenerative Diseases: Autophagy in Neuroinflammation Perspective.- Chapter 9. Neurodegenerative Diseases and Succinate Dehydrogenase: A Therapeutics Avenue for Treatment.- Chapter 10. Fungicidal SDH Inhibitors in Agriculture: Regulation and Future Perspectives.- Chapter 11. Metabolic Disorders and Succinate Dehydrogenase.