Deciphering Cancer Resistance

Nyhet

Mechanisms, Targets, and Emerging Therapies

Häftad, Engelska, 2026

Av Abraham Pedroza, Rosa M. Alvarez-Gomez, Rosa M Alvarez-Gomez

2 169 kr

Kommande

Deciphering Cancer Resistance: Mechanisms, Targets, and Emerging Therapies addresses the critical challenge of treatment resistance in oncology. The book provides a comprehensive examination of the cellular, molecular, and genetic mechanisms behind resistance, unveiling insights from cancer biology and genomics that inform novel therapeutic strategies. Sections explore cutting-edge technologies like CAR-T cell therapy, nanotechnology, and artificial intelligence, highlighting their role in discovering new treatment modalities. Readers will find the latest preclinical and clinical data, including newly FDA-approved therapies, demonstrating their potential to improve patient outcomes.

For academics, this resource consolidates the latest research and clinical developments, aiding researchers, clinicians, and students in staying updated on advancements. It will also be a great guide for graduate studies and research, offering critical insights into drug development and targeted therapies for professionals in the pharmaceutical and biotechnology sectors, ultimately driving progress in cancer treatment.

Provides an in-depth analysis of cellular, molecular, and genetic mechanisms behind cancer treatment resistance
Explores cutting-edge technologies such as CAR-T cell therapy, nanotechnology, and artificial intelligence in addressing resistance
Presents the latest preclinical and clinical data, including newly FDA-approved therapies, to enhance patient outcomes

Produktinformation

Utgivningsdatum2026-08-01
Mått191 x 235 x undefined mm
Vikt450 g
FormatHäftad
SpråkEngelska
SerieNovel approaches to overcome cancer resistance to conventional therapies
Antal sidor330
FörlagElsevier Science
ISBN9780443456596

Tillhör följande kategorier

Biologi inom Naturvetenskap och teknik

Dr. Pedroza is a specialist in molecular biology and cancer research, with a focus on identifying molecular markers associated with treatment resistance in ovarian cancer. His research also explores the role of cellular exosomes in modulating the tumor microenvironment and influencing the response to cisplatin therapy. Dr. Alvarez-Gomez is aspecialist in genetics and cancer risk assessment. Currently, she is the chief of the Hereditary Cancer Clinic at National Cancer Institute (INCAN), Mexico. Dr. Alvarez's multidisciplinary clinical and research program emphasizes the relevance of the translational medicine in diagnosis, treatment and assessment of patients with inherited cancer and their families.

Part I: Molecular and Cellular Mechanisms Underlying Cancer Resistance (Chapters 1-5)1. Molecular Pathways in Cancer Resistance: A Comprehensive Overview2. Role of Tumor Microenvironment in Therapy Resistance3. Epigenetic Modifications and Drug Resistance in Cancer4. Cancer Stem Cells as Drivers of Resistance to Conventional Therapies5. Mechanisms of Immune Escape and Resistance to Immunotherapy in Cancer TreatmentPart II: Emerging Therapeutic Approaches to Overcome Resistance (Chapters 6-13)6. Targeting Epigenetic Regulators: Promising Avenues7. CRISPR and Gene Editing in Combating Drug Resistance8. Synthetic Lethality and PARP Inhibitors in Resistant Tumors9. Role of Nanomedicine in Delivering Targeted Therapies10. Overcoming Resistance to Immunotherapy with Checkpoint Blockade11. Exploiting Tumor Metabolism to Reverse Resistance12. The Role of MicroRNAs and Non-coding RNAs in Therapeutic Resistance13. Overcoming Cancer Resistance: The Role of Emerging CAR-T Cell ApproachesPart III: Clinical Applications and Future Perspectives (Chapters 14-18)14. Biomarker Development for Predicting Therapy Resistance15. Precision Medicine in the Context of Cancer Resistance16. Combination Therapies to Enhance Treatment Efficacy in Resistant Cancers17. AI-Driven Approaches to Overcoming Cancer Resistance18. Future Directions in Overcoming Cancer Resistance: Challenges and Opportunities