Cystic Fibrosis

Bhupendra Prajapati, PhD, is a Professor in the Department of Pharmaceutics at the Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Gujarat, India. He has more than 22 years of academic and research experience and has published more than 250 research and review papers in international and national journals. Under his editorship, five books has been published, and eight book are in progress. He has authored 150 book chapters in the field of novel drug delivery and has published two Indian patents, with another three applications under evaluation. He is a reviewer for high-impact journals and is on the editorial boards of several scientific journals.Rishabha Malviya, PhD, is working as Associate Professor in the Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, India. He has 12 years of research experience. His area of interest includes formulation optimization, nanoformulation, targeted drug delivery, localized drug delivery, and characterization of natural polymers as pharmaceutical excipients. He has authored more than 200 research/review papers for national/international journals of repute. He has 58 patents (19 grants, 38 published, one filed) and many publications in reputed national and international journals. He has received an Outstanding Reviewer Award from Elsevier. He has authored and edited 48 books (Wiley, CRC Press/Taylor and Francis, Springer, River Publisher, IOP Publishing, and OMICS Publishing Group) and authored over 30 book chapters. His name has included in the World Top 2% Scientists list by Stanford University. He is a reviewer, editor, and editorial board member for more than 50 national and international journals of repute. He was an invited author for the magazine Atlas of Science as well as a pharma magazine dealing with B2B industry, Ingredient South Asia. He completed his BPharm at Uttar Pradesh Technical University and MPharm (Pharmaceutics) at Gautam Buddha Technical University, Lucknow Uttar Pradesh, India. His PhD (Pharmacy) work was in novel formulation development techniques.Sonali Sundram, PhD, is Assistant Professor in the School of Medical & Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India. She previously worked as research scientist in a project of the Indian Council of Medical Research at King George Medical University, Lucknow, India. After that, she joined BBDNIIT (Babu Banarasi Das Northern India Institute of Technology), Lucknow. Her PhD (Pharmacy) work was in the area of neurodegeneration and nanoformulation. Her area of interest is neurodegeneration, clinical research, and artificial intelligence. She has authored and edited more than 15 books (Wiley, CRC Press/Taylor and Francis, IOP Publishing, Apple Academic Press/Taylor and Francis, Springer Nature, and River Publisher). She has attended and organized more than 15 national and international seminars, conferences, and workshops. She has more than eight patents national and international to her credit. She has published six SCI-indexed manuscripts with reputed international publishers. She has delivered oral presentations at international conferences organized in different European countries. She completed both here BPharm and MPharm (Pharmacology) at Dr. A.P.J. Abdul Kalam Technical University, Lucknow, India.Akshay Parihar works as an Assistant Professor in the Faculty of Pharmaceutical Sciences, Institute of Chartered Financial Analysts of India University, Himachal Pradesh, India. He is pursuing his PhD at Ganpat University, Mehsana, Gujarat. He earned his MPharm (Pharmaceutics) and BPharm degrees from Bhupal Nobles University, Udaipur, and Rajasthan University of Health Sciences, Jaipur, respectively. He completed an Advanced Post Graduate Program in Clinical Research and Management at Clini India, Pune, and has five years of working experience in academics. He is actively working on novel drug delivery system development and optimization for the increasing solubility of BCS class IV drugs to treat cystic fibrosis.

• Foreword by Dhruv Galgotia Preface 1. Introduction to Cystic Fibrosis 2. Pathophysiological Aspects of Cystic Fibrosis 3. The Role of Microorganisms in Causing Cystic Fibrosis 4. Novel Therapeutic Approaches for Cystic Fibrosis 5. Cystic Fibrosis: Disease and Advanced Drug Delivery Systems 6. Lipid-Nanoparticles in Treating Cystic Fibrosis 7. Regulations for Monitoring and Management of Cystic Fibrosis 8. Aerosol Antibiotics in Management of Cystic Fibrosis 9. Polymeric Nanoparticles in Treating Cystic Fibrosis 10. Medical Devices Used in Cystic Fibrosis 11. Anti-Inflammatory Agents Used in Cystic Fibrosis 12. Challenges for Development of Formulation in Cystic Fibrosis 13. Epigenetic Modifications in CFTR Regulation, Gene Expression and its Impact on Cystic Fibrosis Development 14. Heart Failure in Cystic Fibrosis: Treatment and Prognosis 15. Diagnostic Tools for Cystic Fibrosis 16. Nanomedicine for Cystic Fibrosis