Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis

William L. Hasler, MD is a Professor of Medicine in the Division of Gastroenterology and Hepatology, at the Mayo Clinic in Scottsdale, Arizona. Dr. Hasler’s research focuses on nausea and vomiting and the pathophysiology of gastric motility disorders, and he is an internationally recognized expert in clinical and translational research in CVS and gastroparesis. He serves as a lead advisor to the Rome Foundation and has helped craft the clinical descriptions of CVS and CHS in adults. He also provided pivotal input to develop the first clinical guidelines on the management of CVS in adults David J. Levinthal, MD, PhD is an Assistant Professor of Medicine in the Division of Gastroenterology, Hepatology and Nutrition at the University of Pittsburgh School of Medicine in Pittsburgh, Pennsylvania. Dr. Levinthal’s research focuses on the neural mechanisms of brain-gut interactions and autonomic function, and he is involved in clinical and translational research in CVS. He serves as a Counselor of the American Neurogastroenterology and Motility Society, a Medical Advisor of the Cyclic Vomiting Syndrome Association, and helped to develop the first clinical guidelines on the management of CVS in adults. Thangam Venkatesan, MD is Professor of Clinical Medicine in the Division of Gastroenterology, Hepatology and Nutrition at the Ohio State University in Columbus, Ohio. Patients with CVS travel across the US and beyond to access her well-established CVS center. As a leading CVS expert, she serves as the Chief Medical Advisor of the Cyclic Vomiting Syndrome Association and spearheaded the first clinical guidelines on the management of CVS in adults. She conducts clinical and translational research to develop better therapies for patients with CVS around the world.

• 1. Cyclic vomiting syndrome health expereinces among patients and their caregivers2. Central nervous system pathways of nausea and vomiting3. Clinical features of cyclic vomiting syndrome4. Cyclic vomiting syndrome subtypes - do they provide insight into cyclic vomiting syndrome pathogenesis5. Clinical and pathophysiological relationship between migraines and cyclic vomiting syndrome6. Psychosocial contributors to cyclic vomiting syndrome7. Treatment of acute cyclic vomiting syndrome attacks8. Prevention of recurrent cyclic vomiting syndrome episodes9. Clinical features of cannabinoid hyperemesis syndrome10. How common is cannabinoid hyperemesis syndrome and why is it so hard to diagnose?11. Proposed mechanisms of cannabinoid hyperemesis syndrome - how can cannabinoid pathways both relieve and cause vomiting?12. The curious association of hot-water bathing with cyclic vomiting and cannabinoid hyperemesis syndromes13. Management of cannabinoid hyperemesis syndrome -  is it more than just avoiding cannabis use?14. Role of emergency department in cyclic vomiting syndrome and cannabinoid hyperemesis syndrome care15. What can be accomplished to advance the field?