Prof. Kazuo ChinDepartment of Sleep Medicine and Respiratory Care, Division of Sleep Medicine, Nihon University of Medicine, Tokyo, JapanDepartment of Human Disease Genomics, Center for Genomic Medicine, Graduate School Medicine, Kyoto University, Kyoto, Japan

• Part 1 Epidemiology and social issues.- 1 Epidemiology of Sleep Apnea Syndrome in Adult - How much is  the prevalence of adult patients with sleep apnea at present?.- 2 Epidemiology of SAS in children - What should we know about the prevalence of patients in children with sleep apnea at present?.- 3 OSA, morphology and pathophysiology - Why is the morphology so important in the pathophysiology of obstructive sleep apnea?.- 4 Obstructive sleep apnea and lifestyle diseases - Is there a correlation between sleep apnea and lifestyle diseases?.- Part 2 Treatment and the related problems.- 5 Weight loss and positional therapy - Is it effective weight loss or positional therapy for patients with OSA.- 6 Effect of CPAP therapy on weight changes - How to understand weight changes in patients with OSA following CPAP treatment?.- 7 Comparison of oral appliance and CPAP and problems - What is the position of oral appliance for the treatment of obstructive sleep apnea?.- 8 Implantable Therapy - What is the position of implantable equipment in the treatments for OSA.- 9 Telemedicine in clinical practice of obstructive sleep apnea patients - Is the telemedicine effective in the treatment of OSA patients?.- Part 3 SAS in patients with CVD.- 10 Sleep apnea in patients with atrial fibrillation and heart failure - What should we know about the correlation between sleep apnea syndrome and AF or heart failure?.- 11 SAS in coronary artery disease and stroke - What is known about a possible association between coronary artery disease or stroke and SAS?.- Part 4 The Social issue.- 12 Use of hypnotics - Do you subscribe sleeping pills for insomnia in OSA patients?.- 13 SAS and Driving - What should we know about patients with OSAS and driving?.- Part 5 Topics.-  14 CCHS and PHOX2B - What should we know about the diagnosis and management of patients with CCHS including PHOX2B gene?.- 15 Sleep-disordered breathing associated with neuromuscular diseases - What should we know about sleep-disordered breathing in patients with  neurological disorders?.- 16 Blood pressure, nocturia, and obstructive sleep apnea - What we know about their relationships?.