Current and Future Immunosuppressive Therapies Following Transplantation

Häftad, Engelska, 2012

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This title provides a comprehensive and state-of-the-art summary of current and future immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies.

Produktinformation

Utgivningsdatum2012-09-12
Mått160 x 240 x 22 mm
Vikt604 g
FormatHäftad
SpråkEngelska
Antal sidor388
FörlagSpringer
ISBN9789401038768

Tillhör följande kategorier

Onkologi inom Medicin
Transplantationskirurgi inom Medicin

I. Introduction.- 1. The History of Immunosuppression for Organ Transplantation.- 2. Clinical Trials in Transplant Immunosuppression: What Have We Learned?.- II. Pharmacological Immunosuppression.- 1. Pharmacologic Monitoring of Immunosuppressive Drugs.- 2. Use of Corticosteroids in Kidney Transplantation.- 3. Mycophenolate Mofetil and Azathioprine.- 4. Cyclosporine Formulations.- 5. Tacrolimus.- 6. Sirolimus.- 7. New Agents on the Horizon.- III. Biologicals.- 1. Why Do We Need Induction Therapy?.- 2. Polyclonal Antilymphocyte Therapy.- 3. Monoclonal Antibody Targeting of the T cell Receptor Complex.- 4. Monoclonal Antibody Targeting of IL-2R-Complex.- 5. Monoclonal Antibody Targeting of Adhesion Molecules.- 6. Costimulation Blocade.- 7. Immunomodulatory Function of MHC Peptides.- 8. Tolerance: Is It Time to Move to the Clinic?.- IV. Gene Therapy.- 1. Molecular Medicine in Organ Transplantation: How and When?.- 2. Gene Therapy in Organ Transplantation: Applicabilities and Shortcomings.- 3. Immunomodulation Strategies in Xenotransplantation.