Cryo-electron Tomography

Cryo-electron Tomography: A Journey from Sample Preparation to Data Mining offers a comprehensive guide to the latest state-of-the-art methods and techniques available to researchers. The book begins with a section on sample preparation, considering a range of different sample types including virus-like particles, viruses, bacteria, organoids and tissues, with some chapters dedicated to specific tools like in situ cellular tomography and correlative techniques. The book then moves on to a section on data mining and specific steps and methods, delivering a complete overview of this advancing technique and providing researchers with the knowledge and tools required for their own investigations.

• Provides a detailed overview of cryo-ET sample preparation and data mining protocols and approaches in a single resource
• Includes foundational knowledge underpinning the field
• Explores the latest methods, techniques and recent developments in cryo-ET
• Offers step-by-step guidance to researchers for key procedures
• Written by an international range of experts