COVID-19 Critical and Intensive Care Medicine Essentials

Denise Battaglini is Consultant in Intensive Care and research assistant at San Martino Policlinico Hospital, Genoa, Italy. Dr. Battaglini is attending a PhD in Translational Medicine at the University of Barcelona, Spain. She attended two research fellowships in pneumonia and respiratory physiotherapy at University of Barcelona, Spain, and in neurological and pulmonary critical care at Federal University of Rio de Janeiro, Brazil. Further, Dr. Denise Battaglini is serving representative roles for the Italian Society of Anaesthesia, Analgesia, Resuscitation, and Intensive Care (SIAARTI) and European Society of Intensive Care Medicine (ESICM). She was former national representative of young Anaesthesiologists and Intensivists in SIAARTI and member of national representatives of the European Society of Anaesthesiology (ESA). She is involved in several research projects regarding critical care management of patients with COVID-19, pulmonary diseases, and neurocritical care. Her actual research interests include pulmonary critical care, neurointensive care, and translational medicine.Paolo Pelosi is the Director of Anaesthesia and Intensive Care as well as Regional Poison Control Center at San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy. Prof. Pelosi is also the Director of the Specialty School in Anesthesiology, Reanimation, Critical Care and Pain Medicine at University of Genoa, Italy. He was former president of the European Society of Anaesthesiology (ESA), former president Italian College of Professors in Anesthesiology and Critical Care (CPAR), and the President elect of the Italian Society of Anaesthesia, Analgesia, Reanimation, and Intensive Care (SIAARTI). Prof. Pelosi was awarded of the titles of  Fellow of theEuropean Respiratory Society (FERS) and Fellow of the European Society of Anaesthesiology and Intensive Care (FESAIC). He published more than 750 original papers.

• Part I. Fundamentals of COVID-19.- Introduction and Essential multi-organs pathophysiology.- Part II. Pneumological critical care of COVID-19.- Pathophysiology and phenotypes.- Radiological patterns and lung ultrasound.- Noninvasive mechanical ventilation and conventional oxygen therapy.- Criteria for intubation and ICU admission.- Invasive mechanical ventilation.- Weaning, tracheostomy and chest physiotherapy.- Part III. Neurological manifestations of COVID-19.- Brief pathophysiology.- Clinical characteristics.- Role of noninvasive neuro-monitoring systems and imaging.- Biomarkers.- Management of neurological complications.- Part IV. Cardiovascular manifestations of COVID-19.- Brief pathophysiology.- Echocardiography, electrocardiogram and biomarkers.- Clinical characteristics.- Management.- Part V. Renal manifestations of COVID-19.- Brief pathophysiology.- Clinical features and biomarkers.- Renal replacement therapy.- Part VI. Haemostasis and coagulation in COVID-19.- Brief pathophysiology.- Coagulation disorders and management.- Part VII. Other multi-organs involvement (MODS-CoV-2).- Gastrointestinal manifestations (including hepatic disease).- Nutritional therapy.- Part VIII. Principles of therapy.- Sedation, analgesia, myorelaxants.- Antibiotics, antiretroviral, corticosteroids, other therapies against SARS-CoV-2.- Coagulation and haemostasis.- Rescue therapies.- Part IX. Appendix - Practical Aspects (Figures and Flowcharts).

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