Ajay K. Singh, MB, MRCP, MBA, Renal Division, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, USASushrut S. Waikar, MD, MPH, Renal Division, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, USAPatrick Murray, MDDean of Medicine & Head of SchoolUniversity College Dublin School of Medicine & Medical ScienceDublin, Ireland

• Part I Epidemiology and Diagnosis.- Chapter 1 Epidemiology, Incidence, Risk Factors, and Outcomes of Acute Kidney Injury.- Chapter 2 Definition and Classification of Acute Kidney Injury.- Chapter 3 Diagnostic Approach: Differential Diagnosis, Physical Exam, Lab Tests, Imaging and Novel Biomarkers.- Part II Pathophysiology.- Chapter 4 Overview of Pathophysiology of Acute Kidney Injury: Human Evidence, Mechanisms, Pathological Correlations and Biomarkers, and Animal Models.- Chapter 5  Tubular Physiology in Acute Kidney Injury: Cell Signaling, Injury, and Inflammation.- Part III Clinical Syndromes.- Chapter 6 Contrast-Associated Acute Kidney Injury.- Chapter 7 Acute Kidney Injury and Liver Disease: Incidence, Pathophysiology, Prevention/Treatment, Outcomes.- Chapter 8 Acute Kidney Injury and Cancer: Incidence, Pathophysiology, Prevention/Treatment, Outcomes.- Chapter 9 Drug-Induced Acute Kidney Injury.- Chapter 10 Sepsis and Acute Kidney Injury: Epidemiology, Pathophysiology, Diagnosis, and Management.- Chapter 11 Acute Kidney Failure and Minimal Change Disease.- Chapter 12 Core Concepts: Post-Cardiac Surgery Acute Kidney Injury.- Chapter 13 Rare and Overlooked Causes of Acute Kidney Injury.- Chapter 14 Acute Kidney Injury in Tropics: Epidemiology, Presentation, Etiology, Specific Diseases, and Treatment.- Chapter 15 Pediatric Acute Kidney Injury: Diagnosis, Epidemiology, and Treatment.- Chapter 16 Post-Renal Acute Kidney Injury: Epidemiology, Presentation, Pathophysiology, Diagnosis, and Management.- Chaper 17 Cardiorenal Acute Kidney Injury: Epidemiology, Presentation, Causes, Pathophysiology and Treatment.- Chapter 18 Perioperative (non-cardiac) Acute Kidney Injury: Epidemiology, Pathophysiology, Prevention, and Treatment.- Part IV Management.- Chapter 19  Non-Dialytic Management of Acute Kidney Injury.- Chapter 20 Diuretics in Acute Kidney Injury.- Chapter 21 Emerging Therapies for Acute Kidney Injury: What’s on the Horizon?.- Chapter 22 Dialytic Therapyof Acute Kidney Injury.- Chapter 23 Drug Dosing in Acute Kidney Injury.