Continuous Renal Replacement Therapy

John A. Kellum, MD, MCCM received his medical degree from the Medical College of Ohio. His postgraduate training includes an internship and residency in Internal Medicine at the University of Rochester, NY, and a Fellowship in Critical Care Medicine at the University of Pittsburgh. His research interests span various aspects of Critical Care Medicine, but center in critical care nephrology, sepsis and multi-organ failure. He has authored more than 750 publications and has won several awards for teaching. He lectures widely and has given more than 500 seminars and invited lectures worldwide. Rinaldo Bellomo is Professor of Intensive Care Medicine, University of Melbourne; Honorary Professor of Medicine, Monash University, Co-director of the Australian and New Zealand Intensive Care Research Centre, Director of Intensive Care Research at the Austin Hospital and Senior Research Advisor in Intensive Care Research at the Royal Melbourne Hospital. He has produced >1800 PubMed citedpublications, is the most published biomedical investigator in the history of Australian medicine and the most published intensive care investigator in the world. Claudio Ronco is Director of the Department of Nephrology and Transplantation at the International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy. He has held positions as Director of the Renal Laboratory of research at the Renal Research Institute and Professor of Medicine at the Albert Einstein College of Medicine and Beth Israel Medical Centre of New York in 1999 and 2000. He has co-authored 1246 papers, 65 books and 86 book chapters and has delivered more than 750 lectures at international meetings and universities.

• Chapter 1: The critically ill patient with AKI John A. Kellum and Aditya Uppalapati Chapter 2: History and rationale for CRRT Claudio Ronco and Ilona Bobek Chapter 3: Terminology and Nomenclature Thiago Reis, Claudio Ronco, Rinaldo Bellomo, and John A. Kellum Chapter 4: Basic principles of solute transport Claudio Ronco and Bill Clark Chapter 5: Principles of fluid management in the ICU Rinaldo Bellomo and Sean M. Bagshaw Chapter 6: Indications, timing and patient selection John A, Kellum, Ragavan Murugan, and Mitra Nadim Chapter 7: Biomarkers Lakhmir Chawla and Alexander Zarbock Chapter 8: Extended indications Rinaldo Bellomo Ian Baldwin Chapter 9: Dose adequacy and assessment Zaccaria Ricci, Thiago Reis, Claudio Ronco Chapter 10: Acid-base and electrolytes John A. Kellum Chapter 11: Choosing a therapy Jorge Cerdá and Claudio Ronco Chapter 12: Vascular access Kai Singbartl and Alexander Zarbock Chapter 13: The circuit and the prescription Rinaldo Bellomo and Ian Baldwin Chapter 14: The membrane: size and material Claudio Ronco and Bill Clark Chapter 15: Fluids John A. Kellum and Paul Palevsky Chapter 16: Net Ultrafiltration Rate Ragavan Murugan, John A. Kellum, and Rinaldo Bellomo Chapter 17: Alarms and troubleshooting Zaccaria Ricci, Ian Baldwin, and Claudio Ronco Chapter 18: Maintaining circuit patency Ian Baldwin Chapter 19: Anticoagulation Rinaldo Bellomo and Ian Baldwin Chapter 20: Regional Citrate Anticoagulation Rinaldo Bellomo Chapter 21: Drug dosing on CRRT Sandra Kane-Gill Chapter 22: Pediatrics Dana Fuhrman and Michael L. Moritz Chapter 23: Therapeutic plasma exchange Joseph E. Kiss Chapter 24: MARS Rinaldo Bellomo Chapter 25: Sorbents Gonzalo Ramírez-Guerrero, Claudio Ronco, Thiago Reis, and Dehua Gong Chapter 26: Hybrid therapies Claudio Ronco Chapter 27: Patient Care Quality and Teamwork Kim Whiteman and Fred Tasota Chapter 28: Starting a CRRT program Jorge Cerdá Chapter 29: Billing and Reimbursement Kevin Finkel Chapter 30: Machines Anna Lorenzin and Claudio Ronco Chapter 31: QI (What can go wrong) Rinaldo Bellomo and Ian Baldwin Chapter 32: Training Education Kim Whiteman and Ian Baldwin