This book brings a crucial perspective to the examination of religion and politics in the Middle East and North Africa (MENA) by focusing on the roles that Christian communities play in this region. Acknowledging and exploring their political activity represents a much-needed contribution to the MENA literature, which overwhelmingly focuses on Islam.Through a collection of country case studies utilizing a variety of analytic methods, the contributors to this collection demonstrate how various Christian groups act as rational, strategic political actors seeking to protect and promote the interests of their organizations and members. The cases explored here elaborate upon how Christians in the MENA region navigate their minority status and respond to local ideas of citizenship that often relegate them to second-class status. The chapters also examine how MENA Churches draw on transnational networks to augment their local political influence. This volume is an important work for understanding contemporary politics in the MENA region, and advances the study of religion’s role in politics more generally.The chapters in this book were originally published as a special issue of the journal Religion, State and Society.