This book constitutes the proceedings of the 22nd European Workshop on Performance Engineering, EPEW 2026, held in Grimstad, Norway, during June 24–26, 2026.The 11 full papers included in this volume were carefully reviewed and selected from 11 submissions. The papers cover the following topical sections: Queues and Strategic Behavior; Cyber-Physical Systems and Adaptive Control; Stochastic Modeling and Heavy-Tailed Distributions; and Rare Events and Complex System Analysis.