Del i serien Advances in Experimental Medicine and Biology

Computational Methods for Precision Oncology

Name: Computational Methods for Precision Oncology
SKU: 9783030918354
Price: 2959 SEK
Availability: InStock
Author: Alessandro Laganà
ISBN: 9783030918354

Inbunden, Engelska, 2022

AvAlessandro Laganà

2 959 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt för medlemmar vid köp för minst 249 kr.

Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by the widespread heterogeneity of cancer genomes and drug responses in designing personalized treatments. Chapters provide a comprehensive overview of the computational approaches, methods, and tools that enable precision oncology, as well as related biological concepts. Covered topics include genome sequencing, the architecture of a precision oncology workflow, and introduces cutting-edge research topics in the field of precision oncology. This book is intended for computational biologists, bioinformaticians, biostatisticians and computational pathologists working in precision oncology and related fields, including cancer genomics, systems biology, and immuno-oncology.

Produktinformation

Utgivningsdatum2022-03-02
Mått178 x 254 x 24 mm
Vikt939 g
FormatInbunden
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor336
FörlagSpringer Nature Switzerland AG
ISBN9783030918354

Tillhör följande kategorier

Alessandro Laganà is Assistant Professor of Oncological Sciences at the Icahn School of Medicine at Mount Sinai, NY. Dr. Laganà's main research interests are integrative cancer genomics, cancer network biology and precision oncology. His current research is focused on the treatment of Multiple Myeloma (malignancy of bone marrow plasma cells). He received both his M.Sc. and Ph.D. from the University of Catania in Catania, Italy. He is also the author of the Humana Press title MicroRNA Target Identification: Methods and Protocols (2019).

Part One: Basic Concepts in Precision Oncology.- Chapter 1. Design and Implementation of a precision oncology workflow.- Chapter 2. An overview of cancer genome sequencing.- Chapter 3. Software infrastructures for precision medicine workflows.- Part Two: Current Computational Methods and Tools in Precision Oncology.- Chapter 4. Somatic and germline variant calling from next-generation sequencing data.- Chapter 5. Identification of copy number alterations from next-generation sequencing data.- Chapter 6. Genome-wide discovery of large-scale structural variants from next-generation sequencing data.- Chapter 7. Assessment of microsatellite instability from next-generation sequencing data.- Chapter 8. Computational approaches for the investigation of intra-tumor heterogeneity and clonal evolution from bulk sequencing data.- Chapter 9. Analysis of the transcriptome for precision oncology applications.- Chapter 10. Computational methods for drug repurposing.- Chapter 11. Pathway for analysisfor precision oncology applications.- Chapter 12. Identification of fusion transcripts from RNA-seq.- Chapter 13. Computational resources for the interpretation of variations in cancer.- Chapter 14. Analysis of electronic health records for precision oncology.- Chapter 15. Network approaches for precision oncology.- Chapter 16. Experimental validation of genomic alterations.- Part Three: Advanced Concepts - The Future of Precision Oncology.- Chapter 17. Molecular profiling of liquid biopsies for precision oncology.- Chapter 18. Artificial intelligence for precision oncology.- Chapter 19. Single-cell technologies in precision oncology.- Chapter 20. Computational approaches for precision immuno-oncology.- Chapter 21. Multi-pmics profiling of the tumor microenvironment.- Chapter 22. Epigenetic and precision oncology.- Chapter 23. Next generation knowledge bases to support precision oncology.

Mer från samma författare

Alessandro Laganà, Giovanni Nigita - MicroRNA Target Identification, Inbunden

Nyhet

Del 3056

MicroRNA Target Identification

Alessandro Laganà, Giovanni Nigita

Inbunden, 2026

2 579 kr

MicroRNA Target Identification

Alessandro Laganà

Inbunden, 2019

2 519 kr

Mer från samma serie

Mechanisms of Lymphocyte Activation and Immune Regulation

Sudhir Gupta, William E. Paul, Anthony Fauci

Häftad, 2012

1 439 kr

Frontiers in Modeling and Control of Breathing

Chi-Sang Poon, Homayoun Kazemi, Chi-Sang Poon, Homayoun Kazemi

Inbunden, 2001

2 969 kr

Biology of Taurine

Ryan J. Huxtable, F. Franconi, A. Giotti

Inbunden, 1987

2 869 kr

Molecular Immunology of Complex Carbohydrates

Albert M. Wu, L. Garry Adams

Inbunden, 1988

1 439 kr

Mechanisms of Physical and Emotional Stress

George P. Chrousos, D. Lynn Loriaux, Philip W. Gold

Inbunden, 1989

2 959 kr

Del 281

Fibrinogen, Thrombosis, Coagulation and Fibrinolysis

Chung Yuan Liu, Chung Yuan Liu, Shu Chien

Inbunden, 1991

1 189 kr

Molecular and Cellular Biology Prostate Cancer

Symposium on Molecular and Cellular Biol, James P. Karr, etc.

Inbunden, 1991

1 189 kr

Nutritional and Toxicological Consequences of Food Processing

Mendel Friedman

Inbunden, 1991

2 959 kr

Recombinant Technology in Haemostasis and Thrombosis

Leon W. Hoyer, Leon Ed Hoyer, W.N. Drohan, Leon W. Hoyer, W N Drohan, Leon W Hoyer

Inbunden, 1991

1 189 kr

New Aspects of Human Polymorphonuclear Leukocytes

W.H. Hörl, P.J. Schollmeyer

Inbunden, 1991

2 959 kr

Du kanske också är intresserad av

MicroRNA Target Identification

Alessandro Laganà

Inbunden, 2019

2 519 kr

Nyhet

Del 3056

MicroRNA Target Identification

Alessandro Laganà, Giovanni Nigita

Inbunden, 2026

2 579 kr

Nyhet

Del 7

Fördrivaren

Viveca Sten

Inbunden, 2026

289 kr319 kr

Katarina Wennstam - Moder blod, Inbunden

Nyhet

Del 4

Moder blod

Katarina Wennstam

Inbunden, 2026

269 kr299 kr

Sarah J. Maas - A Court of Splintered Harmony, Häftad

Nyhet

Del 6

A Court of Splintered Harmony

Sarah J. Maas

Häftad, 2026

259 kr

Ruth Kvarnström-Jones - Systrarna på Sophiahemmet, Inbunden

Nyhet

Del 3

Systrarna på Sophiahemmet

Ruth Kvarnström-Jones

Inbunden, 2026

299 kr329 kr

Nyhet

Del 11

Medusa

Lars Kepler

Inbunden, 2026

289 kr319 kr

Nyhet

Allt det blå på himlen

Mélissa Da Costa

Pocket, 2026

79 kr129 kr

Nyhet

Threshing Day (Limited Deluxe Edition)

Rebecca Yarros

Inbunden, 2026

339 kr

Mari Jungstedt - När göken tystnar, Inbunden

Nyhet

Del 1

När göken tystnar

Mari Jungstedt

Inbunden, 2026

289 kr319 kr

Del i serien Advances in Experimental Medicine and Biology

Computational Methods for Precision Oncology

Inbunden, Engelska, 2022

AvAlessandro Laganà

2 959 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt för medlemmar vid köp för minst 249 kr.

Produktinformation

Utgivningsdatum2022-03-02
Mått178 x 254 x 24 mm
Vikt939 g
FormatInbunden
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor336
FörlagSpringer Nature Switzerland AG
ISBN9783030918354

Tillhör följande kategorier

Part One: Basic Concepts in Precision Oncology.- Chapter 1. Design and Implementation of a precision oncology workflow.- Chapter 2. An overview of cancer genome sequencing.- Chapter 3. Software infrastructures for precision medicine workflows.- Part Two: Current Computational Methods and Tools in Precision Oncology.- Chapter 4. Somatic and germline variant calling from next-generation sequencing data.- Chapter 5. Identification of copy number alterations from next-generation sequencing data.- Chapter 6. Genome-wide discovery of large-scale structural variants from next-generation sequencing data.- Chapter 7. Assessment of microsatellite instability from next-generation sequencing data.- Chapter 8. Computational approaches for the investigation of intra-tumor heterogeneity and clonal evolution from bulk sequencing data.- Chapter 9. Analysis of the transcriptome for precision oncology applications.- Chapter 10. Computational methods for drug repurposing.- Chapter 11. Pathway for analysisfor precision oncology applications.- Chapter 12. Identification of fusion transcripts from RNA-seq.- Chapter 13. Computational resources for the interpretation of variations in cancer.- Chapter 14. Analysis of electronic health records for precision oncology.- Chapter 15. Network approaches for precision oncology.- Chapter 16. Experimental validation of genomic alterations.- Part Three: Advanced Concepts - The Future of Precision Oncology.- Chapter 17. Molecular profiling of liquid biopsies for precision oncology.- Chapter 18. Artificial intelligence for precision oncology.- Chapter 19. Single-cell technologies in precision oncology.- Chapter 20. Computational approaches for precision immuno-oncology.- Chapter 21. Multi-pmics profiling of the tumor microenvironment.- Chapter 22. Epigenetic and precision oncology.- Chapter 23. Next generation knowledge bases to support precision oncology.