This book constitutes the thoroughly refereed proceedings of the 10th International Symposium, ISICA 2018, held in Jiujiang, China, in October 2018.The 32 full papers presented were carefully reviewed and selected from 83 submissions. The papers are organized in topical sections on nature-inspired computing; bio-inspired computing; novel operators in evolutionary algorithms; automatic object segmentation and detection; and image colorization; multilingual automatic document classication and translation; knowledge-based articial intelligence; predictive data mining.