CNS Neuroprotection

Häftad, Engelska, 2010

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This volume is a review which presents both a basic science and clinical perspective on neuroprotective approaches to acute and chronic neurodegenerative conditions. Experts from both fields review current areas of neuroprotection. The book describes basic science discovery in stroke research and the application of such research within the pharmaceutical industry leading to the development of neuroprotective drugs.

Produktinformation

Utgivningsdatum2010-12-01
Mått155 x 235 x undefined mm
FormatHäftad
SpråkEngelska
SerieHandbook of Experimental Pharmacology
Antal sidor500
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783642076251

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik
Neurologi och klinisk neurofysiologi inom Medicin
Farmakologi inom Medicin

Section I: Mechanic Approaches to CNS Neuroprotection.- 1 Blocking Excitotoxicity.- 2 Limiting Apoptosis as a Strategy for CNS Neuroprotection.- 3 Reducing Neuroinflammation.- 4 Mitochondrial Approaches to Neuroprotection.- 5 Stabilizing Calcium Homeostasis.- 6 Blocking Nitric Oxide Toxicity.- Section II: Neuroprotective Agents.- 7 Adenosine-Based Approaches to the Treatment of Neurodegenerative Disease.- 8 Sodium and Calcium Channel Blockers.- 9 Neuroprotection by Free Radical Scavengers and Other Antioxidants.- 10 Chemokines and Chemokine Receptors in the Central Nervous System: New Opportunities for Novel Therapeutics in Brain Ischemia and Trauma.- Section III: CNS Delivery of Neuroprotective Therapies.- 11 Ex Vivo Gene Therapy in the Central Nervous System.- 12 Developing Gene-Based Neuroprotection Strategies Using Herpes Amplicon Vectors.- Section IV: Disease Targetily of Newoportective Therapies.- 13 Stroke.- 14 Traumatic Central Nervous System Injury.- 15 Neurohormonal Signalling Pathways and the Regulation of Alzheimer ?-amyloid Metabolism Integrating Basic and Clinical Observations for Developing Successful Strategies to Delay, Retard or Prevent Cerebral Amyloidosis in Alzheimer’s Disease.- 16 Amyotrophic Lateral Sclerosis.- 17 Therapeutics in Huntington’s Disease.