Clostridial Diseases of Animals

The editors Francisco A. Uzal, DVM, FRVC, MSc, PhD, Dipl. ACVP, is a Distinguished Professor of Diagnostic Pathology and Branch Chief of the San Bernardino Laboratory of the California Animal Health and Food Safety at the University of California at Davis in Davis, California, USA. Bruce A. McClane, PhD, FAAM, is a Professor of Microbiology and Molecular Genetics at the University of Pittsburgh School of Medicine in Pittsburgh, Pennsylvania, United States. Iman Mehdizadeh Gohari, DVM, MSc, PhD, is a Research Assistant Professor at the Department of Microbiology and Molecular Genetics at the University of Pittsburgh School of Medicine in Pittsburgh, Pennsylvania, United States. Mauricio A. Navarro, DVM, MSc, PhD, Dipl. ACVP, is an Assistant Professor of Veterinary Anatomic Pathology at the Universidad Austral de Chile in Valdivia, Chile. Michel R. Popoff, DVM, PhD, is a former Associate Professor and Head of the Research Unit of Anaerobic Bacteria and Toxins and the National Reference Center for Anaerobic Bacteria and Botulism at the Institut Pasteur in Paris, France.

• ContributorsPreface 1 The Pathogenic clostridia1 Taxonomic relationships among the clostridia2 General physiologic and virulence properties of the pathogenic clostridia3 Brief description of animal pathogenic clostridia2 Toxins produced by the pathogenis clostridia4 Toxins of histotoxic clostridia: Clostridium chauvoei, Clostridium septicum, Clostridium novyi and Paeniclostridium sordellii5 Toxins of Clostridium perfringens6 Toxins of Clostridioides difficile7 Clostridium botulinum and Clostridium tetani neurotoxins3 Clostridial infections of the gastrointestinal system8 Diseases produced by Clostridium perfringens type A9 Diseases produced by Clostridium perfringens type B10 Diseases produced by Clostridium perfringens type C11 Diseases produced by Clostridium perfringens type D12 Diseases produced by Clostridium perfringens type E13 Diseases produced by Clostridium perfringens type F14 Diseases produced by Clostridium perfringens type G15 Diseases produced by Clostridioides difficile16 Disease caused by Clostridium colinum: Ulcerative enteritis of poultry and other avian species17 Diseases produced by Clostridium spiroforme18 Clostridial abomasitis of ruminants4 Clostridial histotoxic infections19 Blackleg20 Gas gangrene21 Gangrenous dermatitis of poultry22 Bacillary hemoglobinuria23 Infectious necrotic hepatitis24 Tyzzer disease5 Clostridial neurotoxic infections25 Tetanus26 Botulism27 Diseases caused by other clostridia producing neurotoxins6 Animal clostrifial diseases as zoonosis and animals as reservoir of human clostridial pathogens28 Animal clostrifial diseases as zoonosis and animals as reservoir of human clostridial pathogens