Clinical Metabolomics

Methods and Protocols

Häftad, Engelska, 2019

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This detailed volume presents a comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations.

Produktinformation

Utgivningsdatum2019-06-04
Mått178 x 254 x 28 mm
Vikt776 g
FormatHäftad
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor389
FörlagHumana Press Inc.
ISBN9781493985302

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Biokemi inom Naturvetenskap och teknik

Metabolomics as a Tool to Understand Pathophysiological Processes.- Metabolomics in Immunology Research.- LC-MS-Based Metabolomics of Biofluids Using All Ion Fragmentation (AIF) Acquisition.- Lipid Mediator Metabolomics via LC-MS/MS Profiling and Analysis.- UHPSFC/ESI-MS Analysis of Lipids.- LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples.- Serum Testosterone by Liquid Chromatography Tandem Mass Spectrometry for Routine Clinical Diagnostics.- LC-MS/MS Analysis of Bile Acids.- LC-MS/MS Analysis of Triglycerides in Blood-Derived Samples.- LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl Ethanolamide.- Sphingolipid Analysis in Clinical Research.- Shotgun Lipidomics Approach for Clinical Samples.- Establishing and Performing Targeted Multi-Residue Analysis for Lipid Mediators and Fatty Acids in Small Clinical Plasma Samples.- Chemical Isotope Labeling LC-MS for Human Blood Metabolome Analysis.- Direct Infusion-Tandem Mass Spectrometry (DI-MS/MS) Analysis of Complex Lipids in Human Plasma & Serum Using the LipidyzerTM Platform.- Exploratory GC-MS-Based Metabolomics of Body Fluids.- GC-MS Analysis of Short-Chain Fatty Acids in Feces, Cecum Content, and Blood-Derived Samples.- GC-MS Analysis of Medium- and Long-Chain Fatty Acids in Blood Samples.- Analysis of Oxysterols.- Analysis of Metabolites from the Tricarboxylic Acid Cycle for Yeast and Bacteria Samples Using Gas Chromatography Mass Spectrometry.- GC-MS Analysis of Lipid Oxidation Products in Blood, Urine, and Tissue Samples.- Metabolic Profiling of Urine by Capillary Electrophoresis-Mass Spectrometry Using Non-Covalently Coated Capillaries.- CE-MS for the Analysis of Amino Acids.- NMR Analysis of Fecal Samples.- Quantitative Analysis of Central Energy Metabolism in Cell Culture Samples.- Mass Spectrometry Imaging of Metabolites.- Quality Assured Biobanking: The Leiden University Medical Center Model.- Extracting Knowledge from MS Clinical Metabolomic Data: Processing and Analysis Strategies.