This issue of Thoracic Surgery Clinics, guest edited by Dr. Pier Luigi Filosso, is devoted to Clinical Management of Chest Tubes.� Dr. Filosso has assembled expert authors to review the following topics: Chest Tubes Throughout the Centuries: An Overview of Pleural Space Drainage Across History; Generalities of Chest Tubes; Chest Tube Placement After Pulmonary Resection; Thoracic Trauma: Which Chest Tube?; Chest Tube Placement in Pleural Effusions and Pneumothorax; Modern Techniques to Insert Chest Tubes; Suction or Non-suction?: How to Manage a Chest Tube After Pulmonary Resection; When to Remove a Chest Tube?; Indwelling Pleural Catheters: A Clinical Option in Trapped Lung; Errors in Chest Tube Placement; and more!