Inbunden, Engelska, 2026

Click Chemistry in Drug Discovery and Biomedicine

Av Mohmmad Younus Wani, Anthony J. Burke

2809 kr

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Beskrivning

This book provides a comprehensive overview of the principles, mechanisms, and biomedical applications of click chemistry, with a particular focus on its role in accelerating drug discovery and targeted therapeutic development. Beginning with the evolution and foundational concepts of click reactions, it systematically explores their integration into key areas of pharmaceutical research and drug discovery. This book highlights the application of click chemistry in the synthesis of bioactive molecules, cancer drug development, antimicrobial therapies, peptide and antibody engineering, and vaccine discovery. It also examines the emerging uses of click chemistry in diagnostics, imaging technologies, and the creation of biomaterials, scaffolds, and advanced drug delivery systems. This book also discusses bioorthogonal reactions, personalized medicine approaches, and the integration of computational and systems biology techniques to enhance therapeutic precision.Key Features:Explores the fundamental principles and evolving applications of click chemistry in drug discovery and biomedicineDiscusses the role of click chemistry in cancer therapeutics, antimicrobial development, vaccine research, and personalized medicineHighlights the use of click chemistry in diagnostic imaging, drug delivery systems, and tissue engineeringReviews bioorthogonal strategies and computational approaches enhancing targeted therapeutic designExamines the current challenges and future prospects of click chemistry for advancing drug development and precision healthcareThis book serves as an essential resource for researchers and students of pharmaceutical sciences and chemical biology.

Produktinformation

Utgivningsdatum: 2026-12-14
Mått: 210 x 280 x undefined mm
Format: Inbunden
Språk: Engelska
Antal sidor: 344
Förlag: Taylor & Francis Ltd
ISBN: 9781041121220

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Mer information

Mohmmad Younus Wani is an Associate Professor of Organic and Medicinal Chemistry in the College of Science, University of Jeddah, Jeddah, Saudi Arabia. He earned his Ph.D. in Organic and Medicinal Chemistry from Jamia Millia Islamia, New Delhi, India. He completed his postdoctoral training at the University of Coimbra, Portugal, and Texas Therapeutics Institute, UTHealth, Houston, Texas, USA where his research focused on the development of new treatment strategies and non-traditional approaches to combat antimicrobial drug resistance (AMR). With extensive experience in the field of medicinal chemistry and drug discovery, he has authored/co-authored over 90 peer-reviewed research articles, eight books, and has been granted several US patents. He is the recipient of many prestigious honors, awards, and grants. He is a professional member of many scientific societies and is on the editorial board of many reputed scientific journals. Dr. Wani is working at the interface of chemistry and biology to develop novel small molecule inhibitors, new treatment strategies and novel approaches that could circumvent AMR, which is within the ambit of the WHO’s global action plan on antimicrobial resistance.Anthony J. Burke is an Associate Professor (with habilitation 2012, and PhD 1993) of Pharmaceutical Chemistry at the Faculty of Pharmacy, University of Coimbra, and a Chemistry Europe Fellow (class of 2020). He has worked in various institutions, ranging from University College Dublin, Oxford University, ITQB (Oeiras) and at the Chemistry and Biochemistry Department at the University of Évora. In terms of books, articles, editorials, patents, talks amongst others, he has more than 200 outputs. He has been the coordinator of three major projects in the area of chemical synthesis and catalysis and has a key interest in the use of deep eutectic solvents for asymmetric organocatalysis. He has trained more than 70 students, ranging from post-docs to PhD and MSc students. He is the chair of the International Symposium on Synthesis and Catalysis (ISySyCat) conference series and has been on the evaluation panels of numerous international and national grant selection boards. He is also the founder of ChiraTecnics (www.chiratecnics.com).

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