Dr Prabhjot Kaur, is currently an Associate Professor of Pathology, Director , Hematology Laboratory at the Department of Pathology, Dartmouth Hitchcock Medical Center andGeisel School of Medicine at Dartmouth. She initially trained in India with further residency training in anatomic and clinical pathology at the Albany Medical Center, Albany, NY and at the Mayo Clinic, Rochester MN. She has been practicing pathology as faculty for the past 12 years. Her interest beyond pathology include oil/impasto style and acrylic paintings that have been exhibited locally in New Hampshire and also published in an international anthology of art and poetry. She is a mother of two smart millennials who provide several opportunities to learn and live.   Prabhjot Kaur, MDAssociate Professor of PathologyDepartment of PathologyDartmouth Hitchcock Medical Center andGeisel School of Medicine at DartmouthLebanon, NH

• Definition, Epidemiology, Monoclonal B cell lymphocytosis, Morphology , Immunophenotype, Transformation, Gene expression profiling.- Chromosomal aberrations in CLL :Karyotype and FISH.- B cell receptors (BCRs).- Novel mutations in CLL.- Clonal evolution and the Driver/Passenger Mutation Model in CLL.- Prognosis and predictive factors - Hierarchal classification.- MiRNAs.