Chinmedomics

The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine

Inbunden, Engelska, 2015

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Chinmedomics:�The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine�uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM).�This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications.�This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future.

Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method
Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications
Edited by the leading experts of research related to Chinmedomics

Produktinformation

Utgivningsdatum2015-09-29
Mått191 x 235 x 25 mm
Vikt970 g
FormatInbunden
SpråkEngelska
Antal sidor408
FörlagElsevier Science
ISBN9780128031179

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Farmakologi inom Medicin
Fysiologi inom Medicin

Xijun Wang, PhD, is a Professor of Pharmacology of Traditional Chinese Medicine (TCM) and Vice President at Heilongjiang University of Chinese Medicine in China. Dr. Wang has published more than 150 papers in peer-reviewed journals, received the National Science and Technology Progress Award and National Technological Invention Award and holds 20 patents. His research focuses on serum Pharmacochemistry of Traditional Chinese Medicines. By integrating metabolomics with serum Pharmacochemistry of TCM Dr. Wang has developed and established the theory and research methods of Chinmedomics, whereby the clinical efficacy of TCM formulae can be measured and analyzed.

Preface Origin of ChinmedomicsMethods and protocols of ChinmedomicsChinmedomics advancing drug discovery and development from Yinchenhao TangChinmedomics approach dissects therapeutic properties of ShenQiWan acting on ShenYangXu syndromeMetabolic profiling and biomarkers analysis of Jaundice syndromeMetabolic profiling and biomarkers analysis of GanYuPiXU syndromeMetabolic profiling and biomarkers of Yinhuang syndrome and evaluation on Yinchensini TangMetabolite profiling and biomarkers analysis of Jaundice syndrome related animal modelMetabolomic evaluation of hepatoprotective effect of Yinchenhao Tang and its major bioactive constituentsMetabolomics and proteomics elucidation on therapeutic mechanisms of geniposideMetabolic profiling and potential biomarkers of ShenYinXu syndrome and therapeutic effect of Liuweidihuang WanMetabolic profiling of healthy persons treated with Liuweidihuang WanMetabolic profiling and potential biomarkers analysis of ShenYangXu syndromeMetabolic evaluation of ShenQiWan nourishing ShenYangXu syndromeMetabolic profiling and biomarkers analysis of XinQiXu syndromeActive constituents screening based on correlation analysis between marker metabolites and absorbed constituents in Wen-Xin-FormulaTargeted synergism effects of the combined active constituents of Yinchenhao TangMetabolic profiling and biomarkers of type 2 diabetes and effective evaluation of Tianqi Jiangtang capsuleMetabolic biomarkers of alcohol liver damage and intervention effect of Yinchenhao TangMetabolic profiling and biomarkers analysis of insomnia and intervention effects of Suanzaoren decoction and its related active ingredientsMetabolic biomarkers of nonbacterial prostatitis and treatment evaluation of Phellodendri amurensis cortex and its main componentsMetabolic profiling provides a system for understanding of Alzheimer's disease in rats after treatment with Kaixin SanMetabolic profiles delineate the effect of Shengmai San on Alzheimer's disease in rats