Del i serien Handbooks in Pharmacology and Toxicology

Chemical and Structural Approaches to Rational Drug Design

Inbunden, Engelska, 1994

8 279 kr

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This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It details state-of-the-art approaches to pharmaceutical development currently used by some of the world's foremost laboratories. The book features contributors from a variety of fields, new techniques, previously unpublished data, and extensive reference lists.

Produktinformation

Utgivningsdatum1994-11-28
Mått178 x 254 x 20 mm
Vikt680 g
FormatInbunden
SpråkEngelska
SerieHandbooks in Pharmacology and Toxicology
Antal sidor290
FörlagTaylor & Francis Inc
ISBN9780849378188

Tillhör följande kategorier

Tillverkningsteknik inom Naturvetenskap och teknik
Farmakologi inom Medicin

Section I: Chemical Approaches to Rational Drug Design 1. Design, Synthesis and Antitumor Activity of an Inhibitor of Ribonucleotide Reductase 2. The Development of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors 3. The Development of Potent Angiotensin II Receptor Antagonists Using a Novel Peptide Pharmacophore Model 4. Endothelin Structure and Development of Receptor Antagonists 5. Molecular Targeting Chemistry in Rational Drug Design Section II: Structural Approaches to Rational Drug Design 6. The Role of X-Ray Crystallography in Structure-Based Rational Drug Design 7. Biocomputational Approaches to Protein-Based Drug Design 8. Architecture and Design of Zinc Protein-Ligand Complexes 9. Design of Immunomodulatory Peptides Based on Active Site Structures