Cerebrospinal Fluid Rhinorrhea

Raj Sindwani MD, FACS, FRCS(C) is Vice Chairman and Head of the Section of Rhinology, Sinus and Skull Base Surgery of the Head and Neck Institute at the Cleveland Clinic. He is also Co-Director of the Minimally Invasive Cranial Base and Pituitary Program of the Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center and Fellowship Co-Director of the Advanced Rhinology and Skull Base Surgery Program. Dr. Sindwani is currently President-Elect of the Cleveland Clinic Medical Staff and a member of the Board of Governors. Dr. Sindwani is currently the Editor-in-Chief of the American Journal of Rhinology and Allergy, and past Editor-in-Chief of the Yearbook of Otolaryngology. Dr. Sindwani is an established authority on the medical and surgical management of conditions affecting the sinuses and skull base, and he pioneered endoscopic surgical approaches. He has published and lectured extensively in the field of Rhinology and Skull Base Surgery. Christopher R. Roxbury, MD, FARS is an assistant professor and the director of endoscopic skull base surgery in the section of otolaryngology-head and neck surgery at the University of Chicago. Dr. Roxbury is a Fellow of the American Rhinologic Society, where he serves as an active member on several committees. He has published several peer-reviewed articles discussing the epidemiology, management, and postoperative outcomes of patients suffering from rhinologic and anterior cranial base diseases. He serves as an ad hoc editor for several otolaryngology and neurosurgery journals, including International Forum of Allergy and Rhinology, Laryngoscope, American Journal of Rhinology and Allergy, and World Neurosurgery. Dr. Roxbury is a regular speaker at national rhinology and skull base surgery conferences and has also lectured internationally on reconstructive techniques for cerebrospinal fluid leaks.

• PART I Evaluation and Diagnosis of Cerebrospinal Fluid Rhinorrhea1. Categorizing Cerebrospinal Fluid Leaks: A Framework for Understanding2. Evaluation of the Patients with Cerebrospinal Fluid Leaks: History and Physical Examination3. Confirmatory Testing for Cerebrospinal Fluid Rhinorrhea4. Role of Imaging Studies in the Evaluation and Localization of Cerebrospinal Fluid LeaksPART II Cerebrospinal Fluid Physiology and Anatomy of the Cranial Base5. Cerebrospinal Fluid Physiology and Dynamics6. Surgical Anatomy of the Anterior Cranial Fossa7. Surgical Anatomy of the Middle Cranial Fossa8. Surgical Anatomy of the Posterior Cranial FossaPART III Traumatic and Iatrogenic Cerebrospinal Fluid Leaks9. Pathophysiology and Clinical Evaluationof Iatrogenic Cerebrospinal Fluid Rhinorrhea After Sinus Surgery10. Pathophysiology and Clinical Evaluation of Blunt Force and Penetrating Trauma of the Anterior Cranial Base11. Imaging of Anterior Skull Base Trauma12. Surgical Management of Iatrogenic Cerebrospinal Fluid Rhinorrhea13. Surgical Management of Large Traumatic Anterior Cranial Base Defects via Craniotomy14. Postoperative Management of Traumatic Cranial Base DefectsPART IV Spontaneous Cerebrospinal Fluid Leaks and Idiopathic Intracranial Hypertension15. Pathophysiology of Spontaneous Cerebrospinal Fluid Leaks and Their Relationship with Idiopathic Intracranial Hypertension16. Diagnosis and Medical Management of Idiopathic Intracranial Hypertension17. Surgical Management of Refractory Idiopathic Intracranial Hypertension18. Ophthalmologic Evaluation of Idiopathic Intracranial Hypertension19. Radiologic Findings in Idiopathic Intracranial Hypertension20. Evaluation and Management of Congenital Skull Base Defects21. Surgical Management of Spontaneous Cerebrospinal Fluid Leak of the Cribriform Plate22. Surgical Management of Lateral Sphenoid Recess Meningoencephaloceles and Cerebrospinal Fluid Leaks23. Surgical Management of Spontaneous Cerebrospinal Fluid Rhinorrhea Arising from Clival Defects24. Postoperative Management After Cerebrospinal Fluid Leak Repair in Patients with Idiopathic Intracranial HypertensionPART V Endoscopic Cerebrospinal Fluid Leak Repair and Skull Base Reconstruction and After Tumor Surgery25. Clinical Evaluation of the Sellar Mass Patient26. Clinical Evaluation of Patients with Skull Base Malignancies27. Radiologic Evaluation of Skull Base Masses28. Decision Making in Endoscopic Skull Base Reconstruction: A Graduated Approach29.The Nasoseptal Flap: The Workhorse for Skull Base Reconstruction30. Locoregional Pedicled Flap Options for Skull Base Reconstruction31. Sellar Reconstruction After Pituitary Adenoma Resection32. Reconstruction After Transtuberculum and Transplanum Approaches to Suprasellar Pathology33. Endoscopic Reconstruction of Anterior Cranial Fossa Defects34. Endoscopic Reconstruction of Middle Cranial Fossa Defects35. Endoscopic Reconstruction of Posterior Cranial Fossa Defects36. Transorbital and Transfrontal Approaches to Cerebrospinal Fluid Leak Repair37. Free Flap Reconstruction of Skull Base Defects38. Postoperative Management After Reconstruction Following Skull Base Tumor SurgeryPART VI Cerebrospinal Fluid Diversion and Advances in Instrumentation and Biomaterials39. Role of Cerebrospinal Fluid Diversion in Cerebrospinal Fluid Leak Repairs and Skull Base Surgery40. Advances in Endoscopic Visualization and Surgical Navigation41. Powered Instrumentation and Bipolar Technology in Endoscopic Endonasal Skull Base Surgery42. Evolution of Synthetic Graft Materials and Dural Sealants for Cerebrospinal Fluid Leak Repair