Cellular Microbiology

Brian Henderson is Professor of Biochemistry at University College London. He started his research career as a cell biologist, migrating to become an immunologist then pharmacologist with six years experience in the pharmaceutical industry. In the early 1990s studies of bacteria-host interactions identified a bacterial molecular chaperone, chaperonin 60, as a potent signalling molecule able to induce osteoclast formation and bone remodelling. This was Henderson's introduction to protein moonlighting and he has spent the past twenty years exploring the roles of bacterial and human moonlighting proteins in human health and disease.Michael Wilson is a Professor of Microbiology in the Faculty of Biomedical Sciences at University College London and is Director of the Eastman Centre for Microbial Diseases within this university. He holds a PhD in Microbiology from University College Galway, Ireland, a Doctor of Science from the National University of Ireland and is a Fellow of the Royal College of Pathologists. He has written and/or edited eight books and published more than 270 scientific papers in the fields of microbiology and infectious diseases.Rod McNab is the author of Cellular Microbiology: Bacteria-Host Interactions in Health and Disease, published by Wiley.Alistair J. Lax is the author of Cellular Microbiology: Bacteria-Host Interactions in Health and Disease, published by Wiley.

• BACKGROUND TO CELLULAR MICROBIOLOGY. An Introduction to Cellular Microbiology. The Cellular Biology Underlying Prokaryotic-Eukaryotic Interactions. Prokaryotic and Eukaryotic Signalling Mechanisms. Molecular Techniques Defining Bacterial Virulence Mechanisms. PROKARYOTIC-EUKARYOTIC INTERACTIONS IN INFECTION. Bacterial Adhesion to Host Cells. Bacterial Invasion of Host Cells. Bacterial Protein Toxins: Agents of Disease and Probes of Eukaryotic Cell Behaviour. The Innate Immune Response and Bacterial Infections. Acquired Immunity in the Defence Against Bacteria. Future Developments in Cellular Microbiology. Index.

"A splendidly written book... the authors have achieved their goal and the book should be useful to students and researchers in many subject areas." (Microbiology Today, November 2000)"... a timely and extremely welcome textbook...." (Trends in Microbiology, Volume 8, Number 2, February 2000)