Cellular Ecophysiology of Microbe: Hydrocarbon and Lipid Interactions

Tino Krell has studied Biochemistry in Leipzig (Germany) and did his PhD at the University of Glasgow (UK). He was then appointed laboratory head in the R & D Department of Sanofi Pasteur, S.A. in France. In 2004 he moved to Spain to work for the governmental research body CSIC, where he established a laboratory on bacterial sensing and signal transduction. He has investigated molecular mechanisms by which hydrocarbons are sensed by bacteria in the context of their expulsion, degradation or chemotaxis.

• Adaptation to Varying Substrate Concentrations and Mixtures.- Amphiphilic Lipids, Signaling Molecules and Quorum Sensing.- Bacterial Signal Transduction Processes Based on Acetylation.- Biochemistry of Methylation of DNA.- Biofilm Development at Interfaces between Hydrophobic Organic Compounds and Water.- Biofilm Stress Responses Associated to Aromatic Hydrocarbons.- Bioinformatic, Molecular and Genetic Tools for Exploring Genome-wide Responses to Hydrocarbons.- Causes and Biochemistry of DNA Damage by Alkylation.- Chemotaxis to Hydrocarbons.- Cis-Trans Isomerase of Unsaturated Fatty Acids: An Immediate Bacterial Adaptive Mechanism to Cope with Emerging Membrane Perturbation Caused by Toxic Hydrocarbons.- DNA Methylation in Eukaryotes: Regulation and Function.- DNA Methylation in Prokaryotes: Regulation and Function.- Extrusion Pumps for Hydrocarbons: An Efficient Evolutionary Strategy to Confer Resistance to Hydrocarbons.- Fatty Acids as Mediators of Intercellular Signalling.- Feast: Choking on Acetyl-CoA, the Glyoxylate Shunt, and Acetyl-CoA-Driven Metabolism.- Fungi as Transport Vectors for Contaminants and Contaminant-Degrading Bacteria.- Genetics of Sensing, Accessing, and Exploiting Hydrocarbons.- Genomic Response of Pseudomonas putida to Toluene.- Hydrophobic Modifications of Biomolecules: An Introduction.- Kinetics and Physiology at Vanishingly Small Substrate Concentrations.- Lipidation of Other Biomolecules and Functions.- Lipids as Signalling Molecules in Eukaryotes.- Matrix-Hydrophobic Compound Interactions.- Membrane Adaptations to Low Water Two-Phase Bioprocess Systems.- Membrane Composition and Modifications in Response to Aromatic Hydrocarbons in Gram Negative Bacteria.- Microbiology of Oil Fly Larvae.- Microorganism-Hydrophobic Compound Interactions.- Mutagenic Consequences of Alkylation.- Nitrogen Fixation and Hydrocarbon-Oxidizing Bacteria.- One-Component Systems that Regulate the Expression of Degradation Pathways for Aromatic Compounds.- Problems of Feast or Famine: An Introduction:.- Problems of Hydrophobicity/Bioavailability: An Introduction.- Problems of Solventogenicity, Solvent Tolerance: An Introduction.- Production and Roles of Biosurfactants and Bioemulsifiers in Accessing Hydrophobic Substrates.- Protein Alkylation.- Protein Lipidation in Eukaryotes: Biochemistry and Function.- Protein Lipidation in Prokaryotes: Biochemistry and Function.- Protein Methylation in Bacteria.- Sensing, Signaling and Uptake: An Introduction.- Strategies to Increase Bioavailability and Uptake of Hydrocarbons.- Substrate Transport.- Surface Properties and Cellular Energetics of Bacteria in Response to the Presence of Hydrocarbons.- The Family of Two-Component Systems that Regulate Hydrocarbon Degradation Pathways.- The Potential of Hydrocarbon Chemotaxis to Increase Bioavailability and Biodegradation Efficiency.- Toxicity of Hydrocarbons to Microorganisms.- Transcriptional Regulation of Hydrocarbon Efflux Pump Expression in Bacteria.-Ultrastructural Insights into Microbial Life at the Hydrocarbon:Aqueous Environment Interface.- Uptake and Assimilation of Hydrophobic Substrates by the Oleaginous Yeast Yarrowia lipolytica.- Water-Hydrophobic Compound Interactions with the Microbial Cell.