Cellular and Molecular Mechanisms in Alzheimer”s Disease Therapeutics

Volume 1: Cellular Mechanisms

Inbunden, Engelska, 2026

AvPrashant Tiwari,Sunil Kumar Kadiri,Kunjbihari Sulakhiya

2 319 kr

Kommande

As research continues to uncover the complex causes of Alzheimer’s disease, a deeper understanding of its cellular and molecular mechanisms is essential for developing effective therapies. Cellular and Molecular Mechanisms in Alzheimer’s Disease Therapeutics, a two volume set, provides a comprehensive examination of the processes driving disease onset and progression, bringing together leading experts to illuminate key pathways, therapeutic targets, and emerging treatment strategies. Volume 1: Cellular Mechanisms explores the cellular mechanisms underlying Alzheimer’s disease—such as synaptic dysfunction, neuroinflammation, mitochondrial impairment, and protein aggregation—while highlighting their therapeutic implications, including personalized medicine, blood–brain barrier dynamics, and micro RNA-based approaches. Volume 2: Molecular Mechanisms examines AD at the molecular level—covering protein aggregation, cellular dysfunction, and neuroinflammation—while integrating emerging therapies, personalized approaches, and global research efforts to bridge fundamental mechanisms with clinical applications.

Produktinformation

Utgivningsdatum2026-08-18
Mått152 x 229 x undefined mm
FormatInbunden
SpråkEngelska
Antal sidor326
FörlagApple Academic Press Inc.
ISBN9781779641786

Tillhör följande kategorier

Farmakologi inom Medicin
Alzheimer, demens inom Medicin
Cellbiologi inom Naturvetenskap och teknik
Fysiologi inom Medicin

Prashant Tiwari, PhD, is an Associate Professor in the Department of Pharmacology at the College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru, India. He has over a decade of experience in the field of teaching and research related to pharmacology. His expertise includes drug screening, method validation for brain-targeted drug delivery, drug-induced dyskinesia revalidation, and the neuroprotective effects of benzimidazole derivatives. His research has explored the dopaminergic pathway, prolactin inhibition, and neuroprotection, with notable studies on nanoemulsions containing Lepidium sativum oil for Parkinson’s disease and Muntingia calabura leaf extract for Alzheimer’s disease. For his outstanding work, Dr. Tiwari received the Dr. P. D. Patil National Award for Best Thesis in Pharmaceutical Sciences (2022). In addition to his research, Dr. Tiwari has authored five books, edited five books, and co-authored six book chapters. He has filed seven patents, two of which have been granted. He organized a national e-seminar on targeted drug delivery against neurodegenerative diseases, sponsored by the Department of Biotechnology (DBT), Government of India. Dr. Tiwari has been honored with various awards as well. He supervises five PhD students and has guided nine MPharm students. He is also an active member of professional bodies and serves as a peer reviewer for international journals. His research interests span neurodegenerative disorders, drug interactions, pharmacokinetics/pharmacodynamics, and metabolic disorders. He holds a PhD from Siksha O Anusandhan University, Bhubaneswar, and was a fellow of the Indian Council of Medical Research (ICMR), New Delhi, India.Sunil Kumar Kadiri, PhD, is currently working as a Professor in the College of Pharmaceutical Sciences at Dayananda Sagar University, Bengaluru, Karnataka, India. He has 16 years of experience in teaching. His area of interest is neuropharmacology and drug interactions. He has over 50 research and review publications to his credit as well as four books and three patents. He is a professional member of the Association of Pharmaceutical Teachers of India. Dr. Kadiri completed his PhD in Pharmaceutical Sciences at JNTU Hyderabad, Telangana, India.Kunjbihari Sulakhiya, PhD, is working as an Assistant Professor at the Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, Madhya Pradesh, India. He has published over 20 research papers, seven review articles, and more than 10 book chapters. He has received 13 awards and fellowships, including six travel awards to present his research papers at international conferences in the USA, Canada, Japan, France, and Macau. He is a member of various professional societies, including the Indian Academy of Neurosciences, the International Society for Neurochemistry, Asia Pacific Society for Neurochemistry, Association of Pharmaceutical Teachers of India, etc. He is serving as an editorial member and reviewer for various reputed journals. His area of research is pre-clinical research in the field of neuropharmacology. He earned his MPharm and PhD in Pharmacology and Toxicology at the National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India.

Preface 1. Exploring the Cellular and Molecular Mechanisms, Pathogenesis, Etiology, and Complications of Alzheimer’s Disease 2. Epigenetic Alterations in Alzheimer’s Disease: DNA Methylation and Histone Modifications with Non-Coding DNA Involvement 3. Neuroinflammation and Role of Peripheral Immune Cells in Alzheimer’s Disease 4. Blood-Brain Barrier Dysfunction: Relevance to Alzheimer’s Disease Pathology and Challenges and Opportunities in Drug Discovery 5. Interdisciplinary Methods: The Integration of Neurology, Genetics, and Systems Biology Approaches to Comprehend Alzheimer’s Disease 6. Personalized Medicine Approaches Based on Genetic Profiling in the Treatment of Alzheimer’s Disease 7. Integration of Biomarker Data into Clinical Trials and Personalized Treatment Plans 8. Role of Oxidative Stress and Mitochondrial Dysfunction in Progression of Alzheimer’s Disease and Its Emerging Phyto-Therapeutic and Nanomedicinal Interventions 9. MicroRNAs in the Management of Alzheimer’s Disease: Significant Approaches as Diagnostic Biomarkers 10. Cellular Symphony: Harmonizing Therapeutic Approaches for Alzheimer’s Disease Through Targeted Intervention Strategies 11. Exploring the Role of the Gene Mutation in the Management of Alzheimer’s Disease Index