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Khawaja Husnain Haider - Cell-Based Therapies in Regenerative Biology, Inbunden

Inbunden, Engelska, 2027

Cell-Based Therapies in Regenerative Biology

Av Khawaja Husnain Haider

2399 kr

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Beskrivning
This book provides a comprehensive overview of the foundational biology, therapeutic mechanisms, and emerging applications of cell-based therapies in regenerative medicine. It explores the therapeutic role of stem cells in modulating the immune niche and regenerating endocrinological, neurological, cardiovascular, urological, and reproductive systems. The book also delves into the molecular mechanisms associated with cell therapy, including nuclear spin dynamics, dose-response kinetics, and stem cell priming strategies. In addition, the book examines advanced technologies including CAR-engineered immune cells, stem cell-derived biological pacemakers, ECM scaffolds, and exosome-based therapies. Towards the end, the book addresses the ethical and immunological considerations such as HLA editing, allogeneic versus autologous cell therapies, and the use of cell-based interventions in COVID-19-induced ARDS.Key Features:Explores the therapeutic roles of MSCs, iPSCs, and HSCs in tissue repair, immunomodulation, and disease modificationHighlights cutting-edge technologies, including CAR-modified immune cells, biological pacemakers, and exosome-based therapiesExamines organ-targeted regenerative approaches across cardiovascular, neurological, urogenital, endocrine, and reproductive systemsDiscusses mechanistic insights into stem cell behavior, including nuclear spin effects, dose-response kinetics, and priming strategiesIncludes emerging applications in schizophrenia, diabetes, COVID-19 ARDS, ovarian failure, and rare hereditary diseasesThis book is intended for researchers and students of stem cell biology and regenerative medicine.
Produktinformation
  • Utgivningsdatum: 2027-03-17
  • Mått: 210 x 280 x undefined mm
  • Format: Inbunden
  • Språk: Engelska
  • Antal sidor: 496
  • Förlag: Taylor & Francis Ltd
  • ISBN: 9781041144755
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Mer information

Khawaja Husnain Haider is a Professor of Cellular and Molecular Pharmacology (Stem Cell and Gene Therapy), Department of Basic Sciences (Medical Program) at Sulaiman AlRajhi University, Kingdom of Saudi Arabia. Before his current assignment, he served at several prestigious institutions worldwide, including the University of the Punjab, Lahore; Seoul National University; the National University of Singapore; the University of Strathclyde, Glasgow; and the University of Cincinnati, Ohio. He has been included among the Highly Cited Researchers by Clarivate since 2022. More recently, he has been granted Saudi citizenship by Royal decree. He has also served as a Principal Investigator (PI) and Co-PI on multiple National Institutes of Health (NIH)- funded stem cell research projects. He has served on the editorial boards and as an invited reviewer for several respected international journals. His research focuses on using DNA, miRNAs, and stem cells, either alone or in combination, as “drugs,” a topic that has gained popularity in regenerative medicine. He has published extensively on cellular and subcellular preconditioning of stem cells and on using their conditioned media for cell-free therapy. He has published nearly 400 book chapters, abstracts, systematic reviews and meta-analysis, and original research papers in various books and leading international peer-reviewed research journals, including Circulation, Circulation Research, Cardiovascular Research, JCMM, the Journal of Biological Chemistry, Cell Cycle, Basic Research in Cardiology, World J of Stem Cells, World J of Cardiology, Stem Cell Research & Therapy, and Antioxidant Redox Signaling. He has also given numerous presentations and edited 14 books covering various facets of stem cells and their applications, ranging from drug discovery to drug development.

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