Edited by Mark J.D. Griffiths, MRCP, PhD, EDICM, BDICM, Consultant Physician, Adult Intensive Care Unit, Royal Brompton Hospital, London, UK Jeremy J. Cordingley, MBBS, MRCP, FRCA, EDICM, Consultant in Intensive Care Medicine and Anaesthesia, Royal Brompton Hospital, London, UKSusanna S. Price MB, BS, BSc, MRCP, EDICM, PhD, Consultant Cardiologist and Intensivist, Royal Brompton & Harefield NHS Trust, London, UK